Immunological and Non-immunological Factors of Progression of Nephropathies in Children

Czech version

Authors: Ľ. Podracká ¹; M. Šašinka ¹; K. Šebeková ²; J. Šalagovič ⁴; T. Baltesová ¹; A. Böör ³; H. Hrbková ⁵; A. Elbertová ⁶
Authors‘ workplace: Klinika detí a dorastu LF UPJŠ, Košice, 1 prednostka prof. MUDr. Ľ. Podracká, CSc. Ústav klinickej a preventívnej medicíny, Bratislava, 2 prednosta prof. MUDr. R. Dzúrik, DrSc. Ústav patologickej anatómie LF UPJŠ, Košice, 3 prednosta prof. MUDr. A. Böör,
Published in: Čes-slov Pediat 2002; (6): 284-289.
Category:

Overview

Glomerulonephritis (GN)is the most frequent acquired progressive nephropathy of child age.The rate ofprogression up to renal insufficiency depends in addition to the intensity of immune mechanisms also on geneticand metabolic factors.The authors examined in children with chronic GN TH1/TH2 cytokines,renal excretionMCP-1,TGF-beta and PDGF.With the level of creatinaemia TH1 cytokines correlated (p

Key words:
glomerulonephritis in children,immune mechanisms,genetic and metabolic factors

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