Authors: M. Hronek; G. Poljaková Authors‘ workplace: Katedra biologických a lékařských věd, Farmaceutická fakulta UK, Hradec Králové, vedoucí katedry doc. RNDr. V. Semecký, CSc. Published in: Ceska Gynekol 2004; (5): 397-401 Category:
Objective: To summarize the effect of hormonal contraceptive on the level of some vitamins.Subjects: A literature review.Setting: Faculty of Pharmacy, Charles University, Hradec Kralove.Summary: Administration of hormonal contraceptive increase the levels of retinol and 25-hydroxyvitaminD, on the contrary it decreases plasmatic concentration of beta-carotene, transcobalamin,and vitamin E. Results of the evaluation of the level of vitamin C and its interaction withethinylestradiol with consecutive effect are non-uniform. Some alteration of levels of nutrientswas determinated in women during administration of post climacteric hormonal therapy (decreasedplasmatic level of cobalamin and increased level of vitamin D). Alterations of the level ofvitamins are small-scale, administration of this steroid is safe from this point of view.
Key words: hormonal contraceptive, retinol, 25-hydroxyvitamin D, beta-carotene, transcobalamin,vitamin E, vitamin C, pyridoxine
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