Authors: A. Šípek 1; V. Gregor 2; J. Horáček 2; D. Mašátová 3 Authors‘ workplace: Ústav pro péči o matku a dítě, Praha 4-Podolí, ředitel doc. MUDr. J. Feyereisl, CSc. 2Oddělení lékařské genetiky, Fakultní Thomayerova nemocnice, Praha, ředitel Ing. J. Pubrle 3Ústav zdravotnických informací a statistiky České republiky, Praha, ředitelka 1 Published in: Ceska Gynekol 2003; (2): 71-80 Category:
Objective: Analysis of quarterly incidences of selected types of birth defects in the Czech Republicin 1994-2000.Setting: Institute for the Care of Mother and Child, Prague; Department of Medical Genetics,Thomayer Hospital, Prague and Institute of Health Information and Statistics, Prague.Type of study: Retrospective analysis of quarterly data from registers of birth defects in the CzechRepublic.Methods: Processing and analysis of incidences of selected birth defects in the Czech Republic inrelative numbers (per 10 000 liveborn infants). The ratio of observed/expected valueswas calculated.Results: During the period between Jan. 1 1994 and Dec. 31 2000 a total of 654 695 liveborn infantswere born (for 2000 preliminary data). This number included 18 008 infants with one or more birthdefects. The mean incidence of all cases during the observation period was 262.99 per 10 000 liveborninfants. In the analysis the authors discuss in detail also the frequency and its changes of elevenselected types of birth defects.Conclusion: Continous registration and analysis of the incidence of inborn defects are essential asthe basis for evaluation of the influence of the mentioned factors on the incidence of inborn defects.
Key words: inborn defect, population teratology, teratogen, incidence, Czech Republic
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