Authors: Nikola Halačová 1; Miroslava Brndiarová 1; Jakub Zieg 2; Júlia Kvaššayová 1; Alena Szökeová 1,3; Miloš Jeseňák 1 Authors‘ workplace: Klinika detí a dorastu, Jesseniova lekárska fakulta v Martine, Univerzita Komenského v Bratislave, Univerzitná nemocnica v Martine 1; Pediatrická klinika 2. lékařské fakulty UK a Fakultní nemocnice v Motole 2; Ambulancia klinickej farmakológie, Univerzitná nemocnica v Martine 3 Published in: Čes. slov. Farm., 2025; 74, 8-11 doi: https://doi.org/10.36290/csf.2025.025
Kidney transplantation is currently considered the optimal and effective treatment for pediatric patients with end-stage kidney disease. Immunosuppressive treatment is essential throughout the entire functioning period of the transplanted kidney to prevent graft rejection. Aphthous stomatitis with painful ulcerations is a common complication among kidney transplant recipients. A rare cause of this condition is the adverse effect of mycophenolate mofetil, which is part of the most common stable triple combination of immunosuppressive drugs. This article presents a case of multiple painful oral ulcerations induced by mycophenolate mofetil in a 4-year-old boy following a related donor kidney transplant. The lesions resolved promptly after discontinuing the medication.
kidney transplantation – mycophenolate mofetil – aphthous stomatitis – oral ulcerations
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