Obsahové látky
 Philadelphus coronarius L.
							
			
			
																	
									Authors:
											D. Grančai						1; 											V. Vaľko						1; 											E. Švajdlenka						2										
				
									Authors‘ workplace:
											Univerzita Komenského v Bratislave, Farmaceutická fakulta, Katedra farmakognózie a botaniky
						1; 											Veterinární a farmaceutická univerzita v Brne, Farmaceutická fakulta, Ústav přírodních léčiv
						2										
				
									Published in:
					Čes. slov. Farm., 2010; 59, 219-221
					
				
									Category:
					Original Articles
					
				
							
Overview
The paper deals with the isolation and identification of secondary metabolites from Mock Orange leaves (Philadelphus coronarius L.). A methanolic extract was partitioned between ethyl acetate and water. Two flavonoids, kaempferol-3-O-rutinoside and quercetin-3-O-rutinoside (rutin), were isolated from the ethyl acetate fraction. The substances were identified by spectral methods, comparing results with the standards and literature.
Key words:
 Philadelphus coronarius – kaempferol-3-O-rutinoside – quercetin-3-O-rutinoside
Sources
1. Jantová, S., Nagy, M., Ružeková, Ľ., Grančai, D.: Cytotoxic Effects of Plant Extracts from the Families Fabaceae, Oleaceae, Philadelphaceae, Rosaceae and Staphyleaceae. Phytother Res., 2001; 15, 22–25.
2. Jantová, S., Nagy, M., Ružeková, Ľ., Grančai, D.: Antibacterial Activity of Plant Extracts from the Families Fabaceae, Oleaceae, Philadelphaceae, Rosaceae and Staphyleaceae. Phytother Res., 2000; 14, 601–603.
3. Billek, G., Kindl, H.: Über die phenolischen Inhaltstoffe der Familie Saxifragaceae. Monatsch Chem., 1962; 93, 85–98.
4. Grančai, D., Mučaji, P., Nagy, M.: Stanovenie vybraných sekundárnych metabolitov a extraktívnych látok vo Philadelphus coronarius L. Čes. slov. Farm., 1999; 48, 265–267.
5. Mučaji, P., Grančai, D., Nagy, M., Czigleová, S., Ubik, K.: Obsahové látky konárov Philadelphus coronarius L. Farm. Obzor, 2001; 70, 311–314.
6. Mučaji, P., Grančai, D., Nagy, M., Czigleová, S., Buděšínský, M., Ubik, K.: Nepolárne obsahové látky listov Philadelphus coronarius L. Čes. slov. Farm., 2001; 50, 274–276.
7. Vaľko, V., Grančai, D.: Flavonoidové glykozidy vo Philadelphus coronarius L. Farm. Obzor, 2005; 74, 150–152.
8. Pitra, J., Štěrba, J.: Třídění silikagélu pro chromatografii. Chem. Listy., 1963; 57, 389–391.
9. Mabry, T. J., Markham, K. R., Thomas, M. B.: The systematic identification of flavonoids. Springer Verlag 1970, s. 354.
10. Devon, T. K., Scott, A. I.: Handbook of Naturally Occuring Compounds. New York, Inc.: Academic Press 1975, s. 644.
Labels
Pharmacy Clinical pharmacologyArticle was published in
Czech and Slovak Pharmacy
 
					2010 Issue 5
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