Obsahové látky
Philadelphus coronarius L.


Authors: D. Grančai 1;  V. Vaľko 1;  E. Švajdlenka 2
Authors‘ workplace: Univerzita Komenského v Bratislave, Farmaceutická fakulta, Katedra farmakognózie a botaniky 1;  Veterinární a farmaceutická univerzita v Brne, Farmaceutická fakulta, Ústav přírodních léčiv 2
Published in: Čes. slov. Farm., 2010; 59, 219-221
Category: Original Articles

Overview

The paper deals with the isolation and identification of secondary metabolites from Mock Orange leaves (Philadelphus coronarius L.). A methanolic extract was partitioned between ethyl acetate and water. Two flavonoids, kaempferol-3-O-rutinoside and quercetin-3-O-rutinoside (rutin), were isolated from the ethyl acetate fraction. The substances were identified by spectral methods, comparing results with the standards and literature.

Key words:
Philadelphus coronarius – kaempferol-3-O-rutinoside – quercetin-3-O-rutinoside


Sources

1. Jantová, S., Nagy, M., Ružeková, Ľ., Grančai, D.: Cytotoxic Effects of Plant Extracts from the Families Fabaceae, Oleaceae, Philadelphaceae, Rosaceae and Staphyleaceae. Phytother Res., 2001; 15, 22–25.

2. Jantová, S., Nagy, M., Ružeková, Ľ., Grančai, D.: Antibacterial Activity of Plant Extracts from the Families Fabaceae, Oleaceae, Philadelphaceae, Rosaceae and Staphyleaceae. Phytother Res., 2000; 14, 601–603.

3. Billek, G., Kindl, H.: Über die phenolischen Inhaltstoffe der Familie Saxifragaceae. Monatsch Chem., 1962; 93, 85–98.

4. Grančai, D., Mučaji, P., Nagy, M.: Stanovenie vybraných sekundárnych metabolitov a extraktívnych látok vo Philadelphus coronarius L. Čes. slov. Farm., 1999; 48, 265–267.

5. Mučaji, P., Grančai, D., Nagy, M., Czigleová, S., Ubik, K.: Obsahové látky konárov Philadelphus coronarius L. Farm. Obzor, 2001; 70, 311–314.

6. Mučaji, P., Grančai, D., Nagy, M., Czigleová, S., Buděšínský, M., Ubik, K.: Nepolárne obsahové látky listov Philadelphus coronarius L. Čes. slov. Farm., 2001; 50, 274–276.

7. Vaľko, V., Grančai, D.: Flavonoidové glykozidy vo Philadelphus coronarius L. Farm. Obzor, 2005; 74, 150–152.

8. Pitra, J., Štěrba, J.: Třídění silikagélu pro chromatografii. Chem. Listy., 1963; 57, 389–391.

9. Mabry, T. J., Markham, K. R., Thomas, M. B.: The systematic identification of flavonoids. Springer Verlag 1970, s. 354.

10. Devon, T. K., Scott, A. I.: Handbook of Naturally Occuring Compounds. New York, Inc.: Academic Press 1975, s. 644.

Labels
Pharmacy Clinical pharmacology

Article was published in

Czech and Slovak Pharmacy

Issue 5

2010 Issue 5

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