Advances in Enantioselective TLC of Therapeutic Agents


Authors: J. Šubert ;  K. Šlais 1
Authors‘ workplace: Veterinární a farmaceutická univerzita Brno, Farmaceutická fakulta, Ústav chemických léčiv ;  Akademie věd ČR Brno, Ústav analytické chemie 1
Published in: Čes. slov. Farm., 2005; 54, 159-162
Category: Review Articles

Overview

Enantioselective TLC represents a still developing field of analysis of therapeutic agents. In recent years, similarly as in HPLC, mainly direct separations of enantiomers without their preceding derivatization have been published, preferentially using chiral stationary phases, separations with a chiral selector in the mobile phase being less frequent. In the future, a larger choice of commercially available chiral stationary phases could contribute to a more widespread use of enantioselective TLC.

Key words:
enantiomers – TLC – therapeutic agents


Labels
Pharmacy Clinical pharmacology
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