Authors: N. Issa; M. Mlynárová Authors‘ workplace: Štátny ústav pre kontrolu liečiv, Bratislava Published in: Čes. slov. Farm., 2004; , 192-196 Category:
Thin-layer chromatography on silica gel (Merck) was employed to examine potential impuritiespresent in loratadine-containing tablets. A method usable for testing of impurities was elaborated,which suitably supplements the determination of loratadine content using the spectrophotometricmethod in the UV region. The method was validated for selected pharmaceuticals.
Key words: laratadine – thin-layer chromatography (TLC) – impurities – validation
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