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VYUŽITIE KONCEPCIE FARMAKOFÓRU PRIPROJEKTOVANÍ LIEČIV
: M. Smieško; M. Remko
: Katedra farmaceutickej chémie Farmaceutickej fakulty Univerzity Komenského, Bratislava
: Čes. slov. Farm., 1999; , 247-251
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V práci sa diskutuje využitie koncepcie farmakofóru pri projektovaní nových liečiv. Hlavná pozor-nosť sa venuje aplikácii počítačovo podporovaných metód racionálneho projektovania liečiv (CADD)pri objavovaní nových nosných štruktúr.
Klíčová slova:
projektovanie liečiv – farmakofór – databáza – molekulové modelovanie –MEP – konformačná analýza
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Pharmacy Clinical pharmacology
Article was published inCzech and Slovak Pharmacy
1999 Issue 6-
All articles in this issue
- The Use of the Concept of the Pharmacophore in Drug Design
- Chalcones and Their Heterocyclic Analogues as Potential Antifungal Chemotherapeutics
- Production of Anthracene Derivatives by the Elicited Tissue Culture of Rheumpalmatum L.
- The Use of the Elicitor from Pseudomonas aeruginosa on the Production of Flavonoidsby the Culture of Ononis arvensis L. in vitro
- Determination of Selected Secondary Metabolites and Extractive Substances in Phila-delphus coronarius L.
- Effect of Biotic Elicitors on the Production of Flavonoids in Suspension Culture of Bellisperennis L.
- In vitro Effect of Quinolones on Hydrophobicity of Acinetobacter baumannii
- Studies of Local AnaestheticsCL. Models of Dependence of Local Anaesthetic Effectiveness of Basic Esters of Alkoxy-substituted Phenylcarbamic Acids on the Capacity Factor k’
- Substituted Benzo[b]thiophenes with Antileucotriene Activity
- Dissolution and Supersaturation Episodes of Nimodipine in the Aqueous Solutions of theCyclodextrins a-CD, HP-a-CD, M-b-CD, and HP-g-CD
- Czech Pharmaceutical Education under German Occupation in 1939–1945
- Czech and Slovak Pharmacy
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Most read in this issue- The Use of the Concept of the Pharmacophore in Drug Design
- Chalcones and Their Heterocyclic Analogues as Potential Antifungal Chemotherapeutics
- Czech Pharmaceutical Education under German Occupation in 1939–1945
- In vitro Effect of Quinolones on Hydrophobicity of Acinetobacter baumannii
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