VEGF: A KEY PLAYER NOT ONLY IN MACULAR DEGENERATION. A REVIEW
Authors:
J. Slíva
Authors‘ workplace:
Ústav farmakologie, 3. LF UK, Ruská 87,0 00 Praha 10
10
Published in:
Čes. a slov. Oftal., 76, 2020, No. 4, p. 143-145
Category:
Review
doi:
https://doi.org/10.31348/2020/11
Overview
The issue of macular retinal degeneration is one of the key areas of ophthalmology. Recent advances in the targeted delivery of vascular endothelial growth factor (VEGF) suppressants have significantly impacted the patient's prognosis in the form of a significant deceleration in disease progression. Some of the drugs have gradually found their use in other indications (central retinal vein occlusion or diabetic macular edema). The following text gives a brief look at the physiology of VEGF, but not only in the eye, but throughout the human body, particularly in the context of adverse effects resulting from systemic inhibition of its effects.
Keywords:
ranibizumab – bevacizumab – pharmacokinetics – adverse effects – aflibercept – VEGF – vascular endothelial growth factor – pegaptanib
Sources
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OphthalmologyArticle was published in
Czech and Slovak Ophthalmology
2020 Issue 4
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