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Contrast Sensitivity and Higher Order Aberration after Conventional LASIK Treatment


Authors: V. Loukotová;  E. Vlková;  M. Horáčková;  E. Tokošová;  L. Pirnerová;  Z. Hlinomazová;  D. Dvořáková;  J. Němec
Authors‘ workplace: Oční klinika LF MU, FN Brno, přednosta prof. MUDr. E. Vlková, CSc.
Published in: Čes. a slov. Oftal., 65, 2009, No. 5, p. 167-175

Overview

Aim:
The aim of the prospective study was to evaluate photopic high-contrast visual acuity, mesopic contrast sensitivity, and high order aberrations, to compare changes and post-operative development of those parameters and to analyze the dependence among aberrations and contrast sensitivity after conventional LASIK treatment.

Materials and methods:
The authors followed-up patients treated by means of refractive LASIK treatment during the period from November 2006 to November 2007. The authors analyzed 51 eyes (31 patients). The average age of the group was 28.5±5.4 years (range, 18 - 41 years), preoperative average spherical equivalent was -4.95±1.24 D (from -3 to -8,25 D). Before the treatment and 1, 3, 6, and 12 months after LASIK treatment we evaluated the visual acuity (Snellen optotypes), contrast sensitivity under mesopic circumstances (CSV-1000E, VectorVision) and monochromatic aberrations (aberometer Zywave, Bausch & Lomb).

Results:
One year after the treatment the average uncorrected visual acuity was 1.07±0.15, index of effectiveness 0.99, and index of safety 1.02. The contrast sensitivity was in month 12 significantly decreased comparing to the preoperative level at the frequency 12 c/deg, in other already tested frequencies after 3–6 moths did not differed from preoperative values. During the follow-up period the curvature of contrast sensitivity average values was in the upper half of the normal interval range. Conventional LASIK treatment significantly induced the higher order aberration (twice), as well as the spherical aberration (four times). The same level of higher order aberrations root mean square (HOA-RMS), or increased maximally by 0.1 μm was detected by 10 % of cases; the spherical aberration was, compared to the preoperative value, lower, or increased maximally by 0.05 μm in almost one half of the cases. The increase of the higher order aberrations depended directly proportionally to the preoperative value of the spherical equivalent. Before the treatment, the values of total aberrations correlated to the contrast sensitivity of low space frequencies; however, there was not found any correlation between the higher order aberrations and contrast sensitivity. Six months after the LASIK treatment the values of higher order aberrations correlated to the contrast sensitivity except of the lowest frequency tested. The higher order aberrations increased together with decreasing contrast sensitivity. The data from the one-year follow up control did not show statistically significant correlation between the contrast sensitivity and the higher order aberrations. There was not found any correlation between the contrast sensitivity and the spherical aberration at any follow-up control after the surgery.

Conclusion:
Although after the conventional LASIK treatment the curve of mesopic contrast sensitivity was located in the upper half of the normal range, in the medial space frequency it remained decreased comparing to the preoperative stage. The induction of higher order aberrations was twice as much and was directly correlated to the degree of the laser correction. The spherical aberration was four-times higher comparing to the preoperative values and was independent to the level of the initial refractive error. Significant correlation between the contrast sensitivity and the higher order aberrations was not proven.

Key words:
LASIK, higher order aberrations, wavefront technology, contrast sensitivity, quality of vision


Sources

1. Balaszi., G., Mullie, M., Lasswell, L. et al.: Laser in situ keratomileusis with a scanning excimer laser for the correction of low to moderate myopia with and without astigmatism, J Cataract Refract Surg, 2001, 27: 1942-1951

2. Burakgazi, A.Z., Tinio, B., Bababyan, A. et al.: Higher Order Aberrations in Normal Eyes Measured With Three Different Aberrometers, 2006, Journal of Refractive Surgery, 22: 898-903

3. Buzzonetti, L., Petrocelli, G., Valente, P. et al.: Comparison of Corneal Aberration Changes After Laser In Situ Keratomileusis Performed With Mechanical Microkeratome and IntraLase Femtosecond Laser: 1-Year Follow-up, Cornea, 27, 2008, 2: 174-179

4. Fam, H., Lim, K.: Effect of Higher-order Wavefront Aberrations on Binocular Summation, Journal of Refractive Surgery, 2004, 20: S570-S575

5. Feuermannová, A., Komenda, I., Rozsíval, P.: Wavefront analýza – nový směr ve vyšetřování a léčbě refrakčních vad. In Rozsíval, P., Trendy soudobé oftalmologie – svazek 4, Praha, Galén, 2007, s. 37-60

6. Ginsburg, A.P.: Contrast sensitivity: determining the visual quality and function of cataract, intraocular lenses and refractive surgery, Current Opinion in Ophthalmology, 2006, 17: 19-26

7. Hammond, S.D., Puri, A.K., Ambati, B.K.: Quality of vision and patient satisfaction after LASIK, Current Opinion in Ophthalmology, 2004, 15: 328-332

8. Hejcmanová, D., Bytton, L., Langrová, H., Hejcmanová, M.: Vliv transparence nitrooční čočky na rozlišovací schopnost oka, Čes. a slov. Oftal., 60, 2004, 3: 171-179

9. Hejcmanová, M., Horáčková, M., Vlková, E.: Vliv refrakčních zákroků (LASIK) na rozlišovací schopnost oka (první výsledky), Čes. a slov. Oftal., 61, 2005, 3: 205-211

10. Hejcmanová, M., Horáčková, M.: Vliv laserového refrakčního zákroku LASIK na zrakové funkce u myopie, Česká a slovenská Oftalmologie, 62, 2006, 3: 206-217

11. Hiatt, J.A., Grant, C.N., Wachler, B.S.: Establishing Analysis Parameters for Spherical Aberration after Wavefront LASIK, Ophthalmology, 2005, 112: 998-1002

12. Hoffman, R.S., Packer, M., Fine, H.: Contrast sensitivity and laser in situ keratomileusis. In Packer, M., Fine, H., Hoffman, R.S., International ophthalmology clinics, Philadelphia, Lippincott Willliams & Wilkins, 2003, s. 93-100

13. Chalita, M.R., Chavala, S., Xu, M.: Wavefront Analysis in Post-LASIK Eyes and Its Correlation with Visual Symptoms, Refraction and Topography, Ophtalmology, 2004, 111: 447-453

14. Chan, J., Edwards, M., Woo, G. et al.: Contrast sensitivity after laser in situ keratomileusis: one year follow-up, J Cataracta Refract Surg, 2002, 28: 1774-1779

15. Kaiserman, I., Hazarbassanov, R., Varssano et al.: Contrast Sensititivity after Wave Front-Guided LASIK, Ophtalmology, 2004, 111:454-457

16. Kim., A., Chuck, R.S.: Wavefront-guided customized corneal ablation, Current Opinion in Ophthalmology, 2008, 119: 314-320

17. Kohnen, T., Buhren, J., Kasper, T. et al.: Quality of Vision After Refractive Surgery. In Kohnen, T., Koch, D.D., Cataract and Refractive Surgery, Berlin, Springer, 2005, s. 303-314

18. Kulkamthorn, T., Silao, J.N.I., Torres, L. et al.: Wavefront-guided Laser In Situ Keratomileusis in the Treatment of High Myopia by Using the CustomVue Wavefront Platform, Cornea, 27, 2008, 7:787-790

19. Langrová, H., Kyprianou, G.: Nové metody testování zrakové ostrosti, citlivosti na kontrast a citlivosti k oslnění a jejich použití v klinické praxi. In Rozsíval, P., Trendy soudobé oftalmologie – svazek 4, Praha, Galén, 2007, s. 73-98

20. Lawless., M.A., Hodge, Ch.: Wavefrontęs role in corneal refractive surgery, Clinical and Experimental Ophthalmology, 2005, 33: 199-209

21. Lee, H.K., Choe, CH.M., Ma, K.T. et al.: Measurement of Contrast Sensitivity and Glare Under Mesopic and Photopic Conditions Following Wavefront guided and Conventional LASIK Surgery, Journal of Refractive Surgery, 2006, 22: 647-655

22. Lee, H.K., Koh, I.H., Choe, C.M. et al.: Reproducibility of morphoscopic contrast sensitivity testing with the Visual Capacity Analyzer, Journal of Cataract and Refractive Surgery, 2003, 29: 1776-1779

23. Maeda N.: Wavefront technology in ophthalmology, Current Opinion in Ophthalmology, 2001, 12: 294-299

24. Marcos, S., Barbero, S., Llorente, L. et al.: Optical Response to LASIK Surgery for Myopia from Total and Corneal Aberration Measurements, Investigative Ophtalmology & Visual Science, 42, 2001, 13: 3349-3356

25. McDonald, M.B., Carr, J.D., Frantz, J.M. et al.: Laser in situ keratomileusis with for myopia up to –11 diopters with up to –5 diopters of astigmatism with the summit autonomous LADARVision excimer laser systém, Ophthalmology, 2001, 108: 309-316

26. Moreno-Barriuso, E., Lloves, J.M., Marcos, S. et al.: Ocular Aberrations before and after Myopic Corneal Refractive Surgery: LASIK-Induced Changes Measured with Laser Ray Tracing, Investigative Ophtalmology & Visual Science, 42, 2001, 6: 1396-1403

27. Mrochen, M., Kaemmerer, A., Mierdel, P. et al.: Increased higher-order optical aberratios after laser refractive surgery; s problem of subclinical decentration. J Cataract Refract Surg, 2001: 27: 362-369

28. Netto, M.V., Ambrosio, R.,Wilson, S.E.: Pupil size in refractive surgery candidates, J Refract Surg, 2004, 20: 337-342

39. Oshika T., Klyce, S.D., Applegate, R.A. et al.: Comparison of Corneal Wavefront Aberrations After Photorefractive Keratectomy and Laser In Situ Keratomileusis, American Journal of Ophthalmology, 127, 1999, 1: 1-7

30. Oshika, T., Miyata, K., Tokunaga, T. et al.: Higher Order Wavefront Aberrations of Cornea and Magnitude of Refractive Correction in Laser In Situ Keratomileusis, Ophthalmology, 2002, 109: 1154-1158

31. Pepose, J.S., Applegate, R.A.: Making Sense Out of Wavefront Sensing, American Journal of Ophthalmology, 139, 2005, 2: 335-343

32. Peregrin, J., Hejcmanová, D., Svěrák, J.: Kontrastová citlivost a vizus, Čs. Oftal., 1992, 48: 397-400

33. Peregrin, J., Svěrák, J., Hartmann, M. et al.: Citlivost na kontrast u člověka, Čs. Oftal., 1988, 44: 389-399

34. Pérez-Santonja, J.J., Sakla, H.F., Alio, J.L.: Contrast sensitivity after laser in situ keratomileusis, Journal of Cataract and Refractive Surgery 1998, 24: 183-189

35. Pesudovs, K., Marsack, J.D., Donnelly W.J. et al.: Measurin Visual Acuity – Mesopic or Photopic conditions, and High or Low Contrast Letters?, Journal of Refractive Surgery, 20, 2004, 5: S508-S514

36. Puell, M.C, Palomo, C., Ramos, C.S. et al.: Normal Values for Photopic and Mesopic Letter Contrast Sensitivity, Journal of Refractive Surgery, 2004, 20: 484-488

37. Rosen, E.: The Pupil and Refractive Surgery. In Kohnen, T., Koch, D.D., Cataract and Refractive Surgery, Berlin, Springer, 2005, s. 289-302

38. Sakata, N., Tokunaga, T., Miyata, K. et al.: Changes in Contrast Sensitivity Function and Ocular Higher Order Aberration by Conventional Myopic Photorefractive Keratectomy, Japanese Journal of Ophthalmology, 2007, 51: 347-352

39. Salz, J.J., Trattler, W.: Pupil size and corneal laser surgery, Current Opinion in Ophthalmology, 2006, 17: 373-379

40. Seiler, T., Dastjeredi, M.H.: Customized corneal ablation, Current Opinion in Ophthalmology, 2002, 13: 256-260

41. Waheed, S., Krueger, R.: Update on customized excimer ablations: recent developments reported in 2002, Current Opinion in Ophthalmology, 2003, 14:198-202

42. Wang, Z., Chen, J., Yang, B.: Comparison of laser in situ keratomileusis and photorefractive keratectomy to correct myopia from -1.25 to -6.0 diopters, Journal of Refractive Surgery, 1997, 13: 528-534

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