Authors: A. Al-Farzai *; J. Novák **; F. Hubálek ***; P. Češková ***; J. Kvasnička *; F. Langr **** Authors‘ workplace: Oční klinika, Fakultní Nemocnice a Lékařská fakulta v Hradci Králové Univerzity Karlovy v Praze, přednosta prof. MUDr. P. Rozsíval, CSc. **Oční oddělení Krajské nemocnice Pardubice a Ústavu zdravotnických studií UniverzityPardubice, přednosta doc. MUDr. J * Published in: Čes. a slov. Oftal., , 2003, No. 2, p. 91-97 Category:
Thepaper discusses preclinical tests of anewviscoelastic preparation forophthalmosurgery.Experiments revealed that preparationDuo-Bonharen whichcontainshyaluronic acid prepared by bacterial fermentation is suited for clinical tests.After a 24-hour interval following administration into the anterior chamber itdoes not raise intraocular pressure. In experiments it has no side-effects on theeye. The dispersed form in a higher concentration (5 %) adheres verywell to oculartissues and protects them adequately during surgery. The cohesive form in anoptimal concentration (1.5 %) can be rapidly removed from inside the eye. Theproperties of Duo-Bonharen in experiments are comparable with similar viscomaterialswhich are used. The new viscoelastic material Duo-Bonharen appearssuitable for clinical tests in particular for cataract surgery.
Key words: hyaluronic acid, viscomaterial, microsurgery of the eye
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