Electrophysiology in Hypovitaminosis A

Czech version

Authors: J. Svěrák; R. Jebavá; D. Hejcmanová; J. Peregrin; L. Sobotka ^*
Authors‘ workplace: Oční klinika FN LF UK, Hradec Králové, přednosta prof. MUDr. P. Rozsíval, CSc. * Metabolická a gerontologická klinika, přednosta prof. MUDr. Z. Zadák, CSc.
Published in: Čes. a slov. Oftal., , 1999, No. 5, p. 296-298
Category:

Overview

Electroretinographic examinations performed according to the internationalstandard were used in two patients with alimentary hypovitaminosis A. In oneinstance a mentally caused long-term deficiency of dietary vitamin A intake wasinvolved ,in the second instance a fistula from the proximal jejunum into thetransverse colon. In both instances night blindness was reported. The initialvitamin A values were 1.0 and 0.6 micromol/l resp. and after substitution therapythey rose to 2 micromol/l.While the rod and maximal ERG responses improved gradually, the oscillationpotentials remained pathological as regards amplitudes and latencies. We consi-der them therefore a sensitive indicator of the electric sensitivity of the retinaalso in other cases of confirmed or suspected vitamin A deficiency. The existenceand orientation of our metabolic and gerontological clinic provides adequateoportunities for these investigations.

Key words:
hypovitaminosis A, electroretinography, oscillation potentials

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