Journal issue overview Supplementum 3/2019 Clinica...

3

Editorial 2019

6

Uncommon EGFR Mutations in Non-Small Cell Lung Cancer and Their Impact on the Treatment

O. Bílek, M. Holánek, J. Berkovcová, O. Horký, T. Kazda, H. Čoupková, S. Špelda, L. Kristková, M. Zvaríková, J. Podhorec, S. Bořilová, L. Bohovicová, L. Zdražilová Dubská

13

CRISPR-Cas9 as a Tool in Cancer Therapy

P. Zatloukalová, R. Krejčíř, D. Valík, B. Vojtěšek

19

Synthetic Lethality – Its Current Application and Potential in Oncological Treatment

L. Bortlíková, P. Müller, B. Vojtěšek, V. Rak, M. Svoboda

25

Progress in the Utilisation of Organometallic Compounds in the Development of Cancer Drugs

H. Skoupilová, R. Hrstka

34

Overview of Current Findings about the Role of Oestrogen Receptor α in Cancer Cell Signalling Pathways

P. Voňka, R. Hrstka

39

Glycoproteins in the Sera of Oncological Patients

L. Hernychová, L. Uhrík, R. Nenutil, M. V. Novotný

46

Glycosylation as an Important Regulator of Antibody Function

L. Uhrík, L. Hernychová, B. Vojtěšek

56

Protein Ubiquitination Research in Oncology

J. Faktor, M. Pjechová, L. Hernychová, B. Vojtěšek

65

Long Non-Coding RNAs – Current Methods of Detection and Clinical Applications

L. Moráňová, M. Bartošík

72

Oncogenic Viral Protein Interactions with p53 Family Proteins

V. Brychtová, V. Hrabal, B. Vojtěšek

78

Cooperation of Genomic, Transcriptomics and Proteomic Methods in the Detection of Mutated Proteins

F. Zavadil Kokáš, J. Faktor, B. Vojtěšek

Clinical Oncology - Issue Supplementum 3/2019

Editorial

Review

Clinical Oncology