Hypertension and diabetes – malignant cardiometabolic combination

Authors: Hana Rosolová
Authors‘ workplace: Centrum preventivní kardiologie, II. interní klinika LF UK a FN Plzeň
Published in: AtheroRev 2019; 4(2): 87-90
Category: Reviews


Combination of diabetes mellitus (DM) and arterial hypertension (AH) affects about 4–10% of population and their joint prevalence is increasing with age. Those diseases bring high risk of macro- and microvascular complications, i.e. atherosclerotic vascular diseases and diabetic nephropathy, retinopathy and neuropathy. The both diseases are heterogeneous in phenotype, but their risk factors are similar and are present in our life style and environment. Metabolic syndrome re­presents the interstage between AH and type 2 DM (T2DM) and insulin resistance is the background of it. Metabolic syndrome is reversible and therefore its influencing is crucial in primary prevention of T2DM. If AH and T2DM are diagnosed, to start very early non-pharmacological measures and pharmacotherapy for hypertension, diabetes and dyslipidemia are very important. The most appropriate drugs and their combination by the up to date European Guidelines are mentioned.


arterial hypertension – diabetes mellitus – insulin resistance – management of hypertension in diabetics – prevention of macro- and microvascular complications

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Angiology Diabetology Internal medicine Cardiology General practitioner for adults
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