Septic shock in fatal pneumonia caused by Staphylococcus aureus: The significance of producing Pantone-Valentine leukocidine – case report


Authors: Beneš Jiří 1;  Myslivec Ondřej 2;  Laštíková Jarmila 3;  Gabrielová Alice 4;  Petráš Petr 5;  Pantůček Roman 6
Authors‘ workplace: Klinika infekčních nemocí 3. LF UK, FN Na Bulovce, Praha 1;  1. interní oddělení FN Na Bulovce, Praha 2;  Patologicko-anatomické oddělení FN Na Bulovce, Praha 3;  Oddělení klinické mikrobiologie FN Na Bulovce, Praha 4;  Národní referenční laboratoř pro stafylokoky, Státní zdravotní ústav, Praha 5;  Ústav experimentální biologie, Přírodovědecká fakulta MU, Brno 6
Published in: Anest. intenziv. Med., 21, 2010, č. 6, s. 337-341
Category: Intensive Care Medicine - Original Paper

Overview

Necrotizing pneumonia caused by Staphylococcus aureus producing Pantone-Valentine leukocidin (PVL) is a rare but life-threatening disease. Early diagnosis of staphylococcal etiology is necessary for successful treatment. Linezolid is the first choice antibiotic that should be preferred to beta-lactams and vancomycin in this indication.

We report a case of 29-year-old man who was admitted for severe septic shock and incipient pneumonia and died 8 hours after admission despite intensive care. PVL-producing Staphylococcus aureus was isolated from the blood cultures.

Keywords:
sepsis – pneumonia – Staphylococcus aureus – Pantone-Valentine leukocidin


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Labels
Anaesthesiology, Resuscitation and Inten Intensive Care Medicine
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