Prometheus – a new therapeutic option in liver failure in children
Authors:
Hladík Michal 1,2; Zaoral Tomáš 1; Čáp Jiří 3
Authors‘ workplace:
Klinika dětského lékařství Fakultní nemocnice Ostrava
1; Fakulta zdravotních studií, Ostravská univerzita, Ostrava
2; Klinika anesteziologie, resuscitace a intenzivní péče, Transplantcentrum, IKEM
3
Published in:
Anest. intenziv. Med., 21, 2010, č. 4, s. 207-212
Category:
Case Report
Overview
Acute liver failure is a rare but potentially fatal condition with mortality reaching 80–90 %. Dialysis, haemoperfusion and countinuous renal replacement therapy are currently the methods of choice in patients with this critical condition.
Prometheus has been recently introduced in our PICU. This liver replacement device is designed to eliminate toxins produced during the liver failure state. So far two critically ill children – aged 7 years and 15 months – have been treated with Prometheus. Although unfortunately both the patients died of brain oedema, we witnessed a good elimination efficiency of the system. Ideal timing of the initiation of the therapy appears to be a crucial factor.
Keywords:
acute liver failure – child – critical state – Prometheus – King’College Criteria
Sources
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Anaesthesiology, Resuscitation and Inten Intensive Care MedicineArticle was published in
Anaesthesiology and Intensive Care Medicine
2010 Issue 4
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