Cis-atracurium in Clinical Practice:Evaluation of Intubation Conditions,Haemodynamic Changes and Side Effects

Czech version

Authors: P. Nohel; J. Pavlíková
Authors‘ workplace: Anesteziologicko-resuscitační klinika, Fakultní nemocnice U sv. Anny v Brně, přednosta prof. MUDr. Pavel Ševčík, CSc.
Published in: Anest. intenziv. Med., , 2002, č. 4, s. 153-154
Category:

Overview

The authors evaluated the intubating conditions,haemodynamic parameters and possible signs of histamine release after application of therecommended intubating dose of cis-atracurium (3x ED95,i.e.0.15 mg.kg -1 ).At 120 sec after application of the intubating dose the intubating conditionswere assessed as good or excellent in 56 of 60 patients (93.3%).Haemodynamic effects were mild only;no patient had any sign of histamine release.Cis-atracurium is suitable alternative to atracurium.It has better cardiovascular stability,lower histamine release and therefore less side effects thanatracurium.

Key words:
cis-atracurium –muscle relaxants –intubating conditions –side effects

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Article was published in

Anaesthesiology and Intensive Care Medicine

2002 Issue 4