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V čem tkví potenciál monovalentní protilátky u anti-NMDA receptorovou encefalitidu?

What Is the Potential of a Monovalent Antibody in Anti-NMDA Receptor Encephalitis?

7. 11. 2025 Source: proLékaře.cz

Despite standard immunosuppression, anti-NMDAR encephalitis remains associated with high morbidity and prolonged recovery. More targeted treatment options are therefore needed. A preclinical study presents a monovalent humanized antibody that blocks the binding of pathogenic IgG without disrupting receptor function. Its efficacy has been demonstrated across multiple in vitro and in vivo models, including dosage modeling for human patients.

Telemedicína pomáhá zlepšit dostupnost péče o pacienty se srdečním selháním

Telemedicine Helps Improve Access to Care for Patients With Heart Failure

Experienced cardiac nurse Mgr. Monika Černá and cardiologist Prof. MUDr. Jan Krejčí, Ph.D.—both…
5. 11. 2025 Source: proLékaře.cz
Američtí chirurgové umírají častěji na onkologická onemocnění než ostatní lékaři

American Surgeons Die of Cancer More Often Than Other Physicians

A recent study by U.S. researchers sought to map the main causes of death among surgeons. The…
3. 11. 2025 Source: proLékaře.cz
prof. MUDr. Jan Danes, CS.c.

Czech Experience: AI Can Detect Even Very Small Breast Cancers

Women undergoing regular mammography screening can, at some facilities, pay extra to have their…
31. 10. 2025 Source: proLékaře.cz
Jak sebepoškozování dospívajících souvisí se závislostí?

How Is Adolescent Self-Harm Related to Addiction?

Non-suicidal self-injury (NSSI) refers to the deliberate infliction of harm to one’s own body…
29. 10. 2025 Source: proLékaře.cz
Vakcinace proti hepatitidě A se nejvíce zanedbala u osob s onemocněním jater

Vaccination Against Hepatitis A Has Been Most Neglected Among People With Liver Disease

What is the current epidemiological situation regarding COVID-19 and hepatitis A, and what does it…
27. 10. 2025 Source: proLékaře.cz
AI hledá nová antibiotika ve zvířecích jedech

AI Searches for New Antibiotics in Animal Venoms

The development of new antibiotics has stagnated for several decades for a variety of reasons.…
24. 10. 2025 Source: proLékaře.cz
doc. MUDr. Petr Šilhán, Ph.D.

Psychiatry in Ostrava: From a Small Department to a Clinic and New Challenges

After three decades of operation, the psychiatric department of the University Hospital Ostrava has…
22. 10. 2025 Source: proLékaře.cz
Jaké jsou souvislosti mezi gamblingem, depresí a pocity úniku při hře?

What Are the Links Between Gambling, Depression, and Feelings of Escape During Play?

A number of studies have examined the relationship between problem gambling and depressive…
20. 10. 2025 Source: proLékaře.cz
Může AI vyřešit nedostatek zdravotníků v Evropě?

Can AI solve Europe’s healthcare workforce shortage?

According to BMJ Global Health, the global healthcare sector was short approximately 15 million healthcare...
17. 10. 2025 Source: proLékaře.cz
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