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Sport Therapy as Part of Hemophilia Management

27. 10. 2020 Source: Hemophilia with Movement

A study by authors from the University of Wuppertal in Germany specifically examined the impact of a half-year programmed sport therapy on the subjective physical performance and quality of life of individuals with hemophilia.

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EHL preparations have the potential to change the quality of life for people with hemophilia

Within the therapeutic modalities for hemophilia, the current era offers a number of preparations. Newer extended half-life (EHL) replacement therapies can provide hemophiliacs with better protection…
27. 10. 2020 Source: Hemophilia with Movement
COVID_19

Idiopathic Thrombocytopenic Purpura with SARS-CoV-2 Infection

To date, 45 cases of idiopathic (autoimmune) thrombocytopenic purpura (ITP) in individuals with confirmed SARS-CoV-2 infection have been published in the literature. In September 2020, a review…
27. 10. 2020 Source: Immune Thrombocytopenia
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Current Data on the Safety Profile of Baricitinib in the Treatment of Rheumatoid Arthritis

Baricitinib was approved for the treatment of rheumatoid arthritis (RA) in 2017, making it essential and relevant to monitor its safety profile in clinical practice. The analysis of data collected…
26. 10. 2020 Source: Biological Treatment
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Efficacy of Baricitinib in Long-term Therapy of Rheumatoid Arthritis

Baricitinib selectively and reversibly inhibits Janus kinases JAK1 and JAK2 and is used in the treatment of adults with active rheumatoid arthritis (RA). Its safety during long-term administration…
26. 10. 2020 Source: Biological Treatment

Ixekizumab is a Safe Option for Long-Term Treatment of Inflammatory Diseases

Psoriasis, psoriatic arthritis (PsA), and axial spondyloarthritis (SpA) are chronic inflammatory diseases that often require long-term treatment. The current pharmacotherapy of these diseases…
26. 10. 2020 Source: Biological Treatment
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Possibilities of Using Metamizole in the Treatment of Acute Primary Headaches

The aim of the review article by Brazilian authors was to summarize the efficacy and safety of metamizole in the treatment of acute primary headaches, such as migraine, episodic tension-type headache…
26. 10. 2020 Source: Analgesia
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Chemoimmunotherapy in the Treatment of Breast Cancer −⁠ Final Results of the IMpassion130 Study

According to international recommendations, treatment with the immune checkpoint inhibitor atezolizumab in combination with the cytostatic nab-paclitaxel is used for patients with locally advanced or…
25. 10. 2020 Source: Breast Carcinoma
Onkologická pozitivní pacientka

Fixed Combination of Trastuzumab and Pertuzumab for Subcutaneous Administration in Patients with Early Breast Cancer

At a symposium focused on breast cancer, held in December 2019 in San Antonio, Texas, preliminary results of the FeDeriCa clinical study were presented –⁠ comparing the pharmacokinetics, efficacy, and…
25. 10. 2020 Source: Breast Carcinoma
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Dysregulation of microRNA Expression After Treatment with Anti-EGFR Antibodies

A team of researchers from Plzeň decided to verify whether treatment with anti-EGFR antibodies changes the expression of selected microRNAs in patients with metastatic colorectal carcinoma (mCRC).…
22. 10. 2020 Source: Colorectal Cancer
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Panitumumab in 1st Line in Older Patients –⁠ Results of the PANDA Study

The phase II PANDA study evaluated the regimens FOLFOX + panitumumab versus 5-FU + panitumumab in the 1st line treatment of patients with wt-RAS/BRAF metastatic colorectal cancer (mCRC).
22. 10. 2020 Source: Colorectal Cancer
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Dupilumab in the Treatment of Severe Asthma in Real-World Practice

A freshly published French study is the first to confirm the results of clinical trials with dupilumab in patients with severe asthma in real-world practice.
20. 10. 2020 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation
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Treatment of Comorbidities of Atopic Dermatitis in One Go and Where to Refer Candidates for Biologic Therapy

Patients suffering from atopic dermatitis (AD) along with allergic comorbidities typically require a fairly complex pharmacotherapy to manage their difficulties. However, their everyday lives can be…
19. 10. 2020 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Metformin −⁠ A Proven Helper That Effectively Protects the Heart of Diabetics

Metformin is one of the first-line medications for patients with type 2 diabetes. In addition to lowering blood glucose levels, it also affects other metabolic processes in the human body. Its…
19. 10. 2020 Source: Modern Treatment of Diabetes
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Prescription Restrictions on Antidiabetics Authorized for Prescription by General Practitioners -⁠ Status as of October 2020

Diabetes mellitus (DM) has become an increasing problem worldwide in recent years. Long-term complications of DM lead to increased morbidity and mortality in the diabetic population, and their…
15. 10. 2020 Source: Diabetes
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