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Assessment of Infection Risk in Patients with Multiple Sclerosis Treated with Various DMDs

3. 3. 2020 Source: Multiple Sclerosis

Although the increased risk of infections with some disease-modifying drugs (DMDs) is known, we still lack sufficient real-world clinical data to evaluate and compare the risk levels of individual drugs. A Swedish study therefore provides information about these risks with glatiramer acetate, beta interferon, natalizumab, fingolimod, and rituximab in the treatment of multiple sclerosis (MS).

cukrovka, diabetes

Effects of Telmisartan on Vascular Endothelial Functions, Inflammation Parameters, and Insulin Resistance in Patients with CHD and DM

Patients with coronary heart disease (CHD) and diabetes mellitus (DM) often have dysfunctional vascular endothelium, increased inflammatory markers, and insulin resistance. The study presented below…
2. 3. 2020 Source: Sartans in the Treatment of Hypertension
Ledviny a diagnóza

Metabolic Effect of Telmisartan and Candesartan in Kidney Transplant Patients

Increasing cardiovascular risk from complex causes warrants a comprehensive intervention. A prospective randomized crossover study compared the effects of telmisartan and candesartan on lipid and…
2. 3. 2020 Source: Sartans in the Treatment of Hypertension

Favorable effect of linagliptin on renal endothelial functions in patients with type 2 diabetes mellitus

Diabetic nephropathy is the cause of up to 50% of cases of end-stage chronic kidney disease. The main pathological mechanism involved in the development of the early stage of diabetic nephropathy is endothelial...
1. 3. 2020 Source: Diabetes

Monitoring Limits in Prescribing Incontinence Aids is Essential

The amendment to the Public Health Insurance Act, which came into effect in December 2019, brought many changes in the reimbursement of medical aids through prescriptions. The methodology for…
29. 2. 2020 Source: Incontinence
Starší pacientka na konzultaci u lékařky

Comprehensive View on Care for Patients with Urostomy

Thanks to improvements in surgical techniques and shorter hospital stays, patients with a stoma are returning to their home environment and to the care of outpatient doctors sooner. Quality care in…
28. 2. 2020 Source: Ostomy
Starší žena vybírá inkontinenční pomůcku

The Patient Will Feel Comfortable Only with a Properly Chosen Absorption Aid

While before the approval of the amendment to the Public Health Insurance Act, it was possible to issue a prescription only for one type of aid firmly tied to a particular level of incontinence, now…
27. 2. 2020 Source: Incontinence

Initiation of Sacubitril/Valsartan After Acute Decompensation of Chronic Heart Failure: The Sooner, the Better

The recently published analysis of data from the extended open-label follow-up of participants in the PIONEER-HF study clearly pointed out the difference in outcomes and prognosis of patients, which…
27. 2. 2020 Source: Chronic Heart Failure and Lipidology
PL-kycel_panev_obrazek

Pharmacotherapy of Hip Osteoarthritis with Unsaponifiable Soy and Avocado Oil –⁠ Insights from the ERADIAS Study

Unsaponifiable soy and avocado oil is indicated for the symptomatic therapy of hip and knee osteoarthritis. Research primarily focuses on the effectiveness of the drug in patients with knee…
27. 2. 2020 Source: Osteoarthritis Therapy

Continuous Infusion of Tiapride in the Treatment of Hyperactive Delirium –⁠ Case Study

Spanish authors recently published a case study of a young man with pharmacologically unmanageable agitation delirium following multiple injuries from a traffic accident, which resolved within 3 days…
27. 2. 2020 Source: Geriatric Patient

Regular Walking as an Intervention to Support the Quality of Life of Diabetics

Diabetes mellitus (DM), as a chronic and in many cases disabling disease, limits patients in various aspects of their lives. Therefore, it is important to consider the quality of life of diabetics as...
25. 2. 2020 Source: Diabetes
PL_zena_bricho_srdce_tehotenstvi

Transfer of Microbiome from Mother to Child: A Key but Fragile Process

How does the transfer of gut microbiota between mother and child occur? Is this transfer clinically significant, and what factors can disrupt it? These questions are addressed in a 2019 review…
25. 2. 2020 Source: GI, colic and microbiome
:IMPORT-LR:

High pH of Wounds is Associated with Poorer Burn Healing

British scientists have shown that the pH of burn wounds decreases during healing and that higher pH at the second dressing change is associated with poorer healing and the subsequent need for skin grafts....
24. 2. 2020 Source: Wound Healing
Zdroj: https://freerangestock.com/

Chronic Thromboembolic Pulmonary Hypertension –⁠ Editorial

Belicová M. Chronic Thromboembolic Pulmonary Hypertension in a Regional Hospital. Vnitř Lék 2011; 57(2): 140–146.
21. 2. 2020 Source: Pulmonary hypertension (CTEPH, PAH)
Psoriáza na těle pacienta

Persistence of Treatment with Secukinumab and Ixekizumab in Patients with Moderate to Severe Psoriasis

Although IL-17 targeted drugs are increasingly used in the treatment of moderate to severe psoriasis, we currently have limited data on patient persistence with these treatments.
21. 2. 2020 Source: Biological Treatment
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