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News Sonicare Technology as a Modern Means for Good Oral Hygiene

Sonicare technology was developed and introduced to the market by Philips 30 years ago. Since then, the range of products has expanded, and the use of sonic technology has become accessible to a wide spectrum of patients with various problems and needs.

Source: Dental Care 23. 2. 2023

News Ultrasound in a Patch –⁠ Smart System Capable of Monitoring Patient During Regular Activities

A team of scientists from the University of California, San Diego, has developed a miniature autonomous ultrasound system that, when attached to the skin, can visualize tissue located deep beneath the body’s surface. It could be used for continuous monitoring of blood pressure, heart activity, and respiratory parameters in real time, whether during regular activities or intense physical exertion.

Source: 25. 4. 2024

News Carpal Tunnel Syndrome as a Warning Sign of Cardiomyopathy Caused by Transthyretin Amyloidosis

Recent study results suggest that transthyretin amyloidosis is a more common cause of heart failure than previously thought. Early diagnosis and subsequent therapy are key to improving patient prognosis. A comprehensive study evaluating data from the Danish population registry suggests that carpal tunnel syndrome may be one of the initial symptoms of the disease.

Source: Amyloidosis 2. 3. 2023

News When and why to consider the diagnosis of myasthenia gravis in neurological practice, and what treatment options do we currently have?

Myasthenia gravis (MG) is a clinically heterogeneous disease characterized by fluctuating muscle weakness and fatigability that worsens after physical exertion or mental stress. Accurate diagnosis is essential because treatment can lead to permanent remission and full functional capacity of the patient.

Source: Rare Diseases in Neurology 2. 5. 2023

News Association of M2 Haplotype of the Annexin A5 Gene with Recurrent Reproductive Losses

Annexin A5 (ANXA5) is a placental anticoagulant protein that ensures adequate blood supply to the fetus during pregnancy, and its deficiency can increase the incidence of vascular thrombosis in the placenta. Current research shows that the M2 haplotype of the ANXA5 gene may be associated with recurrent reproductive losses and obstetric complications due to placental disorders.

Source: Genetics 5. 5. 2023

News When to Consider Gaucher Disease and How to Diagnose It Early and Correctly

Considering Gaucher disease (GD) as a cause of a patient's problems, especially in the case of splenomegaly and bleeding manifestations, is very important, regardless of age. Screening using the dry blood spot method is available and very simple.

Source: Rare Diseases in Hematology 16. 5. 2023

News Thyroid Disorder Screening in Pregnancy to Be Tested by Pilot Program Starting September

The expectations surrounding the trial launch of the screening program were discussed by Professor Michal Kršek, Chairman of the Czech Endocrinological Society ČLS JEP, on the occasion of the 12th annual “Thyroid Week”.

Source: Thyroid Disorders 8. 6. 2020

News Vaccination Against COVID-19 in Patients Treated With Anticoagulants

Canadian professional societies and the National Health Service (NHS) in the United Kingdom recommend COVID-19 vaccination even for patients treated with anticoagulants. The benefit of vaccination in these patients significantly outweighs the risk of hematoma associated with intramuscular injection. The recommendation applies to both warfarin and direct oral anticoagulants (DOACs).

Source: Anticoagulant Treatment 11. 10. 2021

News Post-COVID-19 Patient Care from the Perspective of Experts Across Fields

For many patients with COVID-19, overcoming the acute phase is crucial, but we now know that the disease may not end there. Some patients even manage the acute stage with very mild symptoms, and significant difficulties arise later in the form of 'post-COVID syndrome.' This issue was discussed in detail at a January webinar by leading experts from various fields.

Source: Cough Therapy 19. 3. 2021

News Why Are Mucolytics Beneficial for Patients with COPD?

Part of the clinical picture of chronic obstructive pulmonary disease (COPD) includes mucus hypersecretion in the airways and its impaired clearance, resulting in a chronic productive cough. Mucus production requires management, just like dyspnea and cough. But what can be expected from mucolytic treatment?

Source: Cough Therapy 15. 4. 2021

News Safety and Tolerance of Metamizole in Postoperative Analgesia in Children

Due to the potential serious side effects of metamizole, the use of this drug in children is often a topic of discussion. Therefore, a prospective multicenter observational non-interventional post-marketing safety study aimed to evaluate the safety of using metamizole in children, with an emphasis on hemodynamic, anaphylactic, or respiratory reactions and agranulocytosis.

Source: Analgesia 16. 3. 2020

News Ocrelizumab in the Treatment of Multiple Sclerosis –⁠ 10-Year Data

Multiple sclerosis (MS) is a lifelong disease with a high risk of permanent disability. Current information on the long-term efficacy and safety of treatment is therefore absolutely essential for the optimal choice of therapeutic agent –⁠ in this case, ocrelizumab.

Source: Neurology - Multiple Sclerosis 20. 2. 2024

News Ketchup Has a Long History –⁠ and Was Originally Intended as Medicine

Behind the globally consumed condiment generating billions in sales lies a story full of radical twists. Ketchup rose to popularity thanks to the alleged medicinal properties of tomatoes, hygiene concerns over perishable foods, and the shift to industrial food production and glass-bottled preservation. Today, it's a staple of nutritionists’ least favorite fast food meals—and has even been dethroned in popularity by salsa. Here's how to advise patients who indulge in ketchup more than they should.

Source: proLékaře.cz 24. 9. 2025

News Excellent effect of sotorasib in a higher line of treatment in a patient with NSCLC with G12C mutation of KRAS –⁠ a case study

We present a case study of an elderly patient with non-small cell lung cancer (NSCLC) treated with the selective KRASG12C inhibitor sotorasib in the 5th line of oncological treatment, but with a very exceptional effect.

Source: Lung Cancer 30. 10. 2024

News First mRNA Treatment for Glycogen Storage Disease Already in Testing Phase

Glycogen storage disease type Ia, also known as von Gierke disease, is a serious inherited disorder with an autosomal recessive inheritance pattern, caused by a deficiency of the enzyme glucose-6-phosphatase. Causal therapy has not been available so far, but this could change in the near future. In a clinical study, the first patient received mRNA therapy aimed at replacing the missing enzyme.

Source: proLékaře.cz 25. 8. 2022