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News If Suicides Were COVID-19... or Why We Still Overlook a Significant Cause of Premature Deaths?

More than a year since the start of the pandemic, the SARS-CoV-2 coronavirus has claimed 2.8 million lives globally, with 127 million recorded cases of COVID-19 (as of March 29, 2021). According to World Health Organization (WHO) data, there are 800,000 suicides annually, with suicide attempts being up to 20 times more frequent, totaling over 16 million. Given our current focus on physical health, are we overlooking the extent and importance of mental health issues in the population? This question has been raised by several experts from different countries in their submission to the February issue of The Journal of Clinical Psychiatry.

Source: Depression and Anxiety 30. 3. 2021

News Fatigue and Quality of Life in Patients with Primary Biliary Cholangitis

Fatigue is the most common symptom of primary biliary cholangitis (PBC). Its occurrence significantly impacts the health-related quality of life of patients.

Source: Primary Biliary Cholangitis 8. 3. 2021

News Why Are Mucolytics Beneficial for Patients with COPD?

Part of the clinical picture of chronic obstructive pulmonary disease (COPD) includes mucus hypersecretion in the airways and its impaired clearance, resulting in a chronic productive cough. Mucus production requires management, just like dyspnea and cough. But what can be expected from mucolytic treatment?

Source: Cough Therapy 15. 4. 2021

News Variability of COPD Symptoms During the Day and Impact on Patients' Morning Routine –⁠ Survey Results

Chronic obstructive pulmonary disease (COPD) is viewed, unlike bronchial asthma, as a condition with a more chronic course and less variability of symptoms throughout the day. The study presented below aimed to clarify whether these patients experience deterioration at certain times of the day and how this affects their daily lives.

Source: COPD 7. 9. 2021

Články časopisu The present and future of metabolic surgery

Author of the article: P. Holéczy, M. Bužga, E. Machytka Source: Rozhledy v chirurgii | 2/2019 21. 2. 2019

News What situations can arise in PBC treatment with obeticholic acid? Answers provided by case studies from real practice at CKTCH

The Hradec Gastroenterology Days 2023 were traditionally held in March at the Educational Center of the Faculty of Medicine, Charles University, in the area of University Hospital Hradec Králové. The expert program included a lecture by MUDr. Libuše Husová, Ph.D., from the Cardio-surgical and Transplant Surgery Center Brno (CKTCH), who highlighted various situations that can arise during the treatment of primary biliary cholangitis (PBC) with three case studies.

Source: Primary Biliary Cholangitis 25. 4. 2023

News Efficacy and Safety of Empagliflozin in Patients with Heart Failure with Preserved Ejection Fraction

Previous studies have shown that the antidiabetic drug empagliflozin reduces the risk of cardiovascular death or hospitalization for heart failure in patients with heart failure with reduced left ventricular ejection fraction (HFrEF), both in diabetics and non-diabetics. The aim of the EMPEROR-Preserved clinical trial was to supplement data on the efficacy and safety of empagliflozin in a population of patients with heart failure with preserved ejection fraction (HFpEF; EF LK > 40%).

Source: Heart Failure 27. 4. 2022

News Summary of Recommendations for the Treatment of Immune Thrombocytopenia in Pregnancy

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a temporary or permanent reduction in the number of platelets, leading to an increased risk of bleeding. It also occurs in 1-5 out of 10,000 pregnant women. We summarize recommendations for the treatment of these patients.

Source: Immune Thrombocytopenia 28. 3. 2021

News Expanded Hemodialysis and Its Impact on Reducing Hospitalization Rates and Medication Usage

The number of patients with end-stage kidney disease is increasing. New approaches and technological advancements in recent decades have contributed to improving hemodialysis treatment. Does the use of so-called expanded hemodialysis lead to better outcomes?

Source: Chronic Kidney Disease 30. 11. 2021

Články časopisu Importance of Centric Relation Registration by the Patients with Complete Dentures
(Practical Report)

Author of the article: I. Voborná, L. Foltasová, K. Francová, Ľ. Harvan Source: Česká stomatologie / Praktické zubní lékařství | 2/2016 10. 6. 2016

Články časopisu What the assessment physician should know about patients on dialysis

Author of the article: E. Pauchová Source: Revizní a posudkové lékařství | 1-2/2019 18. 6. 2019

News ID 360 –⁠ Immunodeficiency in Interdisciplinary Collaboration 2022

For the second time, a two-day meeting titled "ID 360 –⁠ Immunodeficiency in Interdisciplinary Collaboration" took place, this time on March 25–26, 2022, in Prague. Several current topics were discussed during this professional event, which brings together experts who care for patients with primary or secondary immunodeficiencies. The meeting was professionally guaranteed by Prof. MUDr. Anna Šedivá, DSc., from the Institute of Immunology, 2nd Faculty of Medicine, Charles University and University Hospital Motol in Prague.

Source: Primary and Secondary Immunodeficiencies 13. 5. 2022

News Comparison of the Effect of Sonic and Manual Toothbrushes on Dental Plaque and Gingivitis Control

A clinical study on healthy volunteers with mild to moderate gingivitis compared the effectiveness of sonic and manual toothbrushes in terms of dental plaque and gingivitis occurrence. The results of the study showed that the sonic toothbrush outperformed the manual one in all observed parameters.

Source: Dental Care 16. 2. 2023

News Prognostic Significance of Lymphopenia for Stratification of Patients with Follicular Lymphoma

The therapy of follicular lymphoma (FL) is guided by several prognostic indices, such as the Follicular Lymphoma International Prognostic Index (FLIPI). The retrospective analysis of 736 patients with FL presented below introduces a prognostic model combining FLIPI and absolute lymphopenia into an integrated FLIPI-L index. Absolute lymphopenia is crucial for stratifying patient OS and the risk of transformation.

Source: Non-Hodgkin Lymphomas and CLL 17. 3. 2020

News Efficacy and Safety of the Combination of Telmisartan and Amlodipine with Hydrochlorothiazide in the Treatment of Hypertension

The aim of the study by Korean authors was to evaluate the efficacy and tolerability of the triple combination of telmisartan/amlodipine + hydrochlorothiazide (TAH) compared to the combination of telmisartan/amlodipine (TA) alone in patients with essential hypertension who did not respond sufficiently to a 4-week treatment with TA.

Source: Sartans in the Treatment of Hypertension 8. 2. 2022