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News Characteristics of Chronic Wounds Related to Itching During Healing

Itching of wounds during healing is associated with larger wound size, more extensive tissue swelling, and the presence of granulation and necrotic tissue at the base. This was shown by an observational descriptive American study with 200 patients.

Source: Wound Healing 11. 5. 2020

Články časopisu Lung cancer prevention and prevention programs

Author of the article: Lubomír Tulinský Source: Časopis lékařů českých | 4/2023 19. 9. 2023

News Updated Recommendations of the European Society of Cardiology for the Treatment of HCM

Newly published guidelines by the European Society of Cardiology (ESC) bring several updates in the care of patients with cardiomyopathies. In the following excerpt, we focus on new recommendations for the pharmacotherapy of hypertrophic cardiomyopathy (HCM) in the case of left ventricular outflow tract obstruction (LVOTO).

Source: Hypertrophic Cardiomyopathy (HCM) 28. 4. 2024

News Early Implementation of Highly Effective Therapy for Multiple Sclerosis

The ongoing debate about changing the approach to treating relapsing-remitting multiple sclerosis (RRMS) from an escalation strategy to the early implementation of highly effective therapy (HET) is based on the documented high inflammatory activity of the disease in its early stages and the concept of a therapeutic window for its suppression shortly after diagnosis. We bring you a summary of several recent pieces of information about the benefits and safety of HET as an initial treatment for RRMS.

Source: Neurology - Multiple Sclerosis 20. 9. 2023

News Do Beta-Blockers Increase the Risk of Hypoglycemia in Patients with Diabetes and Atherosclerosis?

Given that a large portion of patients with diabetes have proven cardiovascular disease, several clinical studies or their subsequent analyses address the effects of beta-blockers in these patients. One such analysis was the post-hoc analysis of the TECOS study, which among other things, attempted to evaluate the connection between the use of beta-blockers in type 2 diabetics with proven atherosclerotic cardiovascular disease and the incidence of hypoglycemic episodes.

Source: Cardiovascular Continuum 18. 5. 2020

News Pregabalin in the Hands of a General Practitioner

A recent Cochrane systematic review by authors from Oxford University examined the effect of pregabalin in the treatment of postherpetic neuralgia and diabetic neuropathy –⁠ conditions that general practitioners frequently encounter in their practice. Is pregabalin a suitable choice in these indications?

Source: Neuropathic Pain 18. 2. 2020

News The Immune System in the Pathophysiology of ITP

From the perspective of the pathophysiology of immune thrombocytopenia (ITP), it appears that the etiology of this disease is very complex and involves both antibody and cellular immunity.

Source: Immune Thrombocytopenia 9. 4. 2022

News Negative Symptoms of Schizophrenia and Their Assessment

Schizophrenia is a serious psychiatric disorder with a prevalence of up to 1%. It can manifest with both negative and positive symptoms. We briefly summarize the clinical assessment and rating scales of negative symptoms in the following text.

Source: Schizophrenia and Antipsychotics 14. 7. 2021

Články časopisu Rare diseases in the year 2019 –⁠ the Czech and international context

Author of the article: Milan Macek jr. Source: Časopis lékařů českých | 1/2019 4. 4. 2019

Články časopisu Variability of osteogenesis imperfecta manifestations depending on gender: case report

Author of the article: Štěpán Jakub, Kužma Martin, Killinger Zdenko, Payer Juraj Source: Clinical Osteology | 1/2019 26. 8. 2019

News Why Do People Lose Weight Differently on GLP-1RA? The NBEA Gene Was Investigated

Glucagon-like peptide-1 receptor agonists (GLP-1RA) show promising anti-obesity effects, but their efficacy varies among individuals. A newly published study examined the role of the NBEA (neurobeachin) gene in weight loss while using these drugs, analyzing two large cohorts of real-world patients.

Source: 13. 8. 2025

News A Look at Tongue and Its Care from the Perspective of Western and Traditional Chinese Medicine

The tongue is a valuable diagnostic tool used in both Traditional Chinese Medicine (TCM) and Western medicine. While the approaches to tongue care between these two medical systems differ significantly, both recognize the tongue's ability to reflect an individual's overall health. Although these approaches may seem contradictory, with proper application, they can complement each other.

Source: Dental Care 6. 9. 2023

News What has clinical research on the effects of inosin pranobex revealed, and what does it mean for practice?

Inosin pranobex, as an antiviral drug that modulates cellular and humoral immunity, is used in the treatment of many viral infections. It is employed in diseases caused by herpetic viruses, Epstein-Barr virus (EBV), cytomegalovirus, or in immunodeficient states, especially in cases of cellular immunity disorders. What insights has clinical research offered on this matter?

Source: Viral infections 16. 2. 2023

News Psilocybin Approved as of January 1. What Does This Mean in Practice?

As of January 1, 2026, a new legal framework has come into effect in the Czech Republic allowing the limited therapeutic use of psilocybin in patients with severe mental health conditions. This represents the first systematic step in translating the results of long-term clinical research on psychedelics into healthcare practice. How does this change clinical practice, and what should physicians know even if they do not provide this therapy themselves?

Source: 2. 2. 2026

News Possibilities of Using Metamizole in the Treatment of Acute Primary Headaches

The aim of the review article by Brazilian authors was to summarize the efficacy and safety of metamizole in the treatment of acute primary headaches, such as migraine, episodic tension-type headache (ETTH), cluster headache, and unclassified primary pain in adults and children.

Source: Analgesia 26. 10. 2020