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Ureteroscopic Biopsy of Upper Urinary Tract Tumors: Endoscopic and Cytologic Techniques


Authors: D. H. Bagley;  K. A. Healy;  N. Kleinmann;  M. Bibbo
Authors‘ workplace: Department of Urology, Thomas Jefferson University
Published in: Urol List 2012; 10(2): 26-30

Overview

Ureteroscopic biopsy is an essential step in the diagnosis of upper urinary tract tumors. Alternative moda­lities including voided urine and contrast imaging have proven inaccurate for diagnosis. Systematic “no touch” ureteroscopic techniques should be used to survey the involved upper tract. Tumor biopsy may be most efficiently performed with a flat wire basket or cup forceps. Brushes do not provide an adequate sample. All specimens should be delivered fresh in normal saline to the Cytopathology laboratory as soon as possible for tissue preservation. Samples are then prepared using the Cytospin technique, and a cell block is also prepared if any macroscopically visible tissue is present.

Key words:
ureteroscopy, ureter, tumor, biopsy, cytology


Sources

1. Rife CC, Farrow GM, Utz DC. Urine cytology of transitional cell neoplasms. Urol Clin North Am 1979; 6(3): 599–612.

2. Zimmerman RL, Bagley DH, Hawthorne C et al. Utility of the Bard BTA Test in Detecting Upper Urinary Tract Transitional Cell Carcinoma from Ureteroscopic Biopsy. Urology 1998; 51(6): 956–959.

3. Johannes JR, Nelson E, Bibbo M et al. Voided urine fluorescence in situ hybridization testing for upper tract urothelial carcinoma surveillance. J Urol 2010; 184(3): 879–882.

4. Fritz GA, Schoellnast H, Deutschman HA et al. Multiphasic multidetector – row CT (MDCT) in detection and staging of transitional cell carcinomas of the upper urinary tract. Eur Radiol 2006; 16(6): 1244–1252.

5. Ito Y, Kikuchi E, Tanaka N et al. Preoperative hydro­nephrosis grade independently predicts worse pathological outcomes in patients undergoing nephro­ureterectomy for upper tract urothelial carcinoma. J Urol 2011; 185(5): 1621–1626.

6. Keeley FX, Bibbo M, Bagley DH. Ureteroscopic treatment and surveillance of upper urinary tract transitional cell carcinoma. J Urol 1997; 157(5): 1550–1565.

7. Williams SK, Denton KJ, Minervini A et al. Corre­lation of upper tract cytology, retrograde pyelo­graphy, ureteroscopic appearance and ureteroscopic biopsy with histologic examination of upper tract transitional cell carcinoma. J Endourol 2008; 22(1): 71–76.

8. El-Hakim A, Weiss GH, Lee BR et al. Correlation of ureteroscopic appearance with histologic grade of upper tract transitional cell carcinoma. Urology 2004; 63(4): 647–650.

9. Bagley DH, Grasso M. Ureteroscopic Laser Treat­ment of Upper Urinary Tract Neoplasms. World J Urol 2010; 28(2): 143–149.

10. Abdel-Razzak OM, Ehya H, Cubler-Goodman A et al. Ureteroscopic Biopsy in the Upper Urinary Tract. Urology 1994; 44(3): 451–457.

11. Tawfiek ER, Bibbo M, Bagley DH. Ureteroscopic Biopsy: Technique and Specimen Preparation. Urology 1997; 50(1): 117–119.

12. Hudson RG, Conlin MJ, Bagley DH. Ureteric Access with Flexible Ureteroscopes: Effect of the Size of the Ureteroscope. BJU Int 2005; 95(7): 1043–1044.

13. Johnson JB, Portela D, Grasso M. Advanced ure­tero­scopy: Wireless and sheathless. J Endourol 2006; 20(8): 552–555.

14. Abdel-Razzak OM, Ehya H, Cubler-Goodman A et al. Ureteroscopic biopsy in the upper urinary tract. Urology 1994; 44(3): 451–457.

15. Keeley FX, Kulp DA, Bibbo M et al. Diagnostic Accu­racy of Ureteroscopic Biopsy in Upper Tract Transitional Cell Carcinoma. J Urol 1997; 157(1): 33–37.

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Paediatric urologist Urology
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