#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Sexual diferentiation disorders


Authors: J. Kříž
Authors‘ workplace: Klinika dětské chirurgie 2. LF UK a FN Motol, Praha
Published in: Urol List 2007; 5(1): 12-15

Overview

The aim of my article is to summarize the findings about the physiology of human sexual development and describe the types of intersexuality, their patogeneses, genotypes, phenotypes and the treatment strategies. Abnormal sex differentiations are divided against the type of inner gonad.

Key words:
normal sex differentiation, intersexuality, female pseudohermaphroditism, true hermaphroditism, male pseudohermaphroditism, gonadal dysgenesis


Sources

1. Wiener JS, Gonzales Jr ET. Intersex. Curr Opin Urol 1996; 6: 320326.

2. Smith DP, Felker RE, Noe HN, Emerson DS, Mercer B. Prenatal diagnosis of genital anomalies. Urology 1996; 47: 114117.

3. Mandell J, Bromlay B, Peters CA, Benacerraf BR. Prenatal sonographic detection of genital malformations. J Urol 1995; 153: 19941996.

4. Mercado AB, Wilson RC, Cheng KC et al. Prenatal treatment and diagnosis of congenitaladrenal hyperplasia owing to steroid 21hydroxylase deficiency. J Clin Endocrinol Metab 1995; 80: 20142020.

5. Blahoš J. Sexuální diferenciace a její poruchy. In: Blahoš J, Bleha O (eds). 2. vyd. Endokrinologie. Praha: Avicenum 1998: 238252.

6. Berkmen F. Persistent Müllerian duct syndrom with or without transverse testicular ectopia and testis tumors. BJU 1997; 79(1): 122126.

7. Clarnette TD, Sugita Y, Hutson JM. Genital anomalies in human and animal models reveal the mechanisms and hormones governing testicular descent. BJU 1997; 79(1): 99112.

8. Hutson JM. A biphasic model for the hormonal control of testicular descent. Lancet 1985; 24: 419421.

9. Lisá L. Poruchy sexuální diferenciace. Cesk Pediatr 1996; 51(3): 171173.

10. Whitaker RH, Ranslay PG. Intersex. In: Whitaker RH (ed). Current Perspectives in Paediactric Urology. London: SpringerVerlag 1989: 7886.

11. Conte FA, Grumbach MM. Abnormalities of Sexual Differentiation. In: Tanagho EA, McAninch JW (eds). Smith´s General Urology. Norwalk: Appleton and Lange1988: 610627.

Labels
Paediatric urologist Urology
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#