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What can be expected from venetoclax + azacitidine (VEN+AZA) in acute myeloid leukaemia (AML) – results from VIALE-A and post-hoc analyses
Authors: Ľ. Minařík
Authors‘ workplace: I. interní klinika – klinika hematologie, VFN v Praze BIOCEV, 1. LF UK, Vestec
Published in: Transfuze Hematol. dnes,32, 2026, No. 1, p. 22-27.
Category: Review/Educational Papers
doi: https://doi.org/10.48095/cctahd202605Overview
In 2025, the combination of azacitidine (AZA) and venetoclax (VEN) is the standard treatment for older patients with acute myeloid leukaemia (AML) who are not candidates for intensive induction chemotherapy. VEN+AZA has been shown to increase complete remission rates and prolong overall survival. The current treatment regimen is based on the results of the VIALE-A study.
Keywords:
acute myeloid leukaemia (AML) – non-intesive therapy – venetoclax (VEN) – azacitidine (AZA)
Sources
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Prohlášení o konfliktu zájmů
Příprava rukopisu byla podpořena firmou Abbvie.
Do redakce doručeno dne: 18. 11. 2025.
Přijato po recenzi dne: 26. 1. 2026.
MUDr. Ľubomír Minařík, PhD.
I. interní klinika – klinika hematologie
VFN v Praze
U nemocnice 499/2
128 08 Praha 2
BIOCEV
1. LF UK
Průmyslová 595
252 50 Vestec
e-mail: lubomir.minarik@vfn.cz
Labels
Haematology Internal medicine Clinical oncology
Article was published inTransfusion and Haematology Today
2026 Issue 1-
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- Treatment of multiple myeloma with manifestations of light chain deposition disease; complete remission with minimal residual disease negativity following treatment with daratumumab, dexamethasone, and lenalidomide – a case report and a review of the literature
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