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Long-term storage and disposal of cryopreserved grafts – recommendations of the Transplant Section of the Czech Society of Haematology


Authors: D. Lysák 1;  M. Karas 1;  P. Jindra 1;  P. Sedláček 2;  Z. Kořístek 3;  T. Kozák 4;  E. Faber 5;  M. Trněný 6;  P. Žák 7;  P. Měřička 7;  M. Krejčí 8;  R. Pacasová 9;  A. Vítek 10;  R. Pytlík 10
Authors‘ workplace: Hematologicko-onkologické oddělení Fakultní nemocnice Plzeň 1;  Klinika dětské hematologie a onkologie, Fakultní nemocnice Motol, Praha 2;  Klinika hematoonkologie, Fakultní nemocnice Ostrava 3;  Interní hematoonkologická klinika, Fakultní nemocnice Královské Vinohrady, Praha 4;  Hemato-onkologická klinika, Fakultní nemocnice Olomouc 5;  I. interní klinika, Všeobecná fakultní nemocnice, Praha 6;  IV. Interní hematologická klinika, Fakultní nemocnice Hradec Králové 7;  Interní hematologická a onkologická klinika, Fakultní nemocnice Brno 8;  Transfuzní a tkáňové oddělení, Fakultní nemocnice Brno 9;  Ústav hematologie a krevní transfuze, Praha 10
Published in: Transfuze Hematol. dnes,24, 2018, No. 4, p. 298-303.
Category:

Overview

Cryopreservation of haematopoietic stem cells represents a common method used to support autologous transplantation or to process allogeneic collections. Most transplant centres are struggling with an increasing number of unused long-term stored transplants on one hand and the absence of generally accepted rules for their disposal on the other. The goal of the recommendations is to offer a set of measures to ensure the long-term storage and eventual disposal of cryopreserved products and to try and harmonize these at national level.

Key words:

graft – cryopreservation – disposal – storage


Sources

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3. Donnenberg AD, Koch EK, Griffin DL, et al. Viability of cryopreserved BM progenitor cells stored for more than a decade. Cytotherapy 2002;4:157–163.

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8. Olivieri J, Pierelli L, Introna M, et al. GITMO (Gruppo Italiano Trapianto di Midollo Osseo) – SIDEM (Società Italiana di Emaferesi e Manipolazione Cellulare) Working Group on SCU Disposal. Kinetics of the use of cryopreserved autologous stem cell grafts: a GITMO-SIDEM survey. Cytotherapy 2014;16:101–110.

9. Perseghin P, Marchetti M, Pierelli L, et al. Società Italiana di Emaferesi e Manipolazione Cellulare; Gruppo Italiano Trapianto Midollo Osseo; Centro Nazionale Trapianti. A policy for the disposal of autologous hematopoietic progenitor cells: report from an Italian consensus panel. Transfusion 2014;54:2353–2360.

10. Devadas SK, Khairnar M, Hiregoudar SS, et al. Is long term storage of cryopreserved stem cells for hematopoietic stem cell transplantation a worthwhile exercise in developing countries? Blood Res 2017;52:307–310.

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Labels
Haematology Internal medicine Clinical oncology
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