The Therapeutic Exchange Erythrocyapheresis in MethemoglobinemiaCaused by Eugenol Poisoning - First Experience in the Czech Republic
Authors:
J. Pták 1; R. Kula 2
Authors‘ workplace:
Krevní centrum Fakultní nemocnice s poliklinikou, Ostrava 2Klinika anesteziologie a resuscitace Fakultní nemocnice s poliklinikou, Ostrava
1
Published in:
Transfuze Hematol. dnes,, 2003, No. 2, p. 69-72.
Category:
Overview
The authors describe the case of a pacient who was parenterally administered eugenol (clove oil). Theclinical picture was dominated by methemoglobinemia, cyanosis and low hemoglobin saturation byoxygen (66-76%). In view of a severe tissue hypoxia, which was refractory to oxygenotherapy, erythrocytapheresiswas performed. The substitution included 12 transfusion units of deleukocyted erythrocyteconcentrates with the mean hematocrite 0.60 (3,400 ml), irradiated by ionising radiation at thedose of 32 Gy, administered via a transfusion set. The remaining fraction of erythrocytes with pathologicalhemoglobin was 20%. In the course of the intervention, a substantial increase of hemoglobinsaturation by oxygen developed (90%) and no untoward reaction was noticed.
Key words:
exchange erythrocytapheresis, methemoglobinemia, eugenol
Labels
Haematology Internal medicine Clinical oncologyArticle was published in
Transfusion and Haematology Today
2003 Issue 2
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