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Atypical findings in the diagnostics of precancer and cancer of cervix: case reports


Authors: Leopold Rotter 1;  Pavla Rotterová 2;  Michal Michal 2;  Robert Hudeček 1
Authors‘ workplace: Gynekologicko-porodnická klinika LF MU a FN Brno, přednosta prof. MUDr. P. Ventruba, DrSc., MBA 1;  Bioptická laboratoř s. r. o., Plzeň 2
Published in: Prakt Gyn 2014; 18(2): 145-148
Category: Oncogynecology: Case report

Overview

With the implementation of prevention programs, especially cytological screening (oncology exfoliative cytology – OC), in developed countries incidence of cervical cancer is declining. Further decline will be recorded, vaccination against human papillomaviruses (HPV). Early detection of dysplasia and cervical cancer remains a major health problem, yet. The aim of the article is presentation of possible discrepancies in the results of non-invasive methods and biopsies in cervical lesions diagnosis. These cases can appear in daily gynecologic practice.

Key words:
cervical carcinoma – HPV – human papillomavirus – oncology exfoliative cytology


Sources

1. WHO. International Agency for Research on Cancer: GLOBOCAN project. Dostupné z: <http://globocan.iarc.fr/Default.aspx>.

2. Epidemiologie nádorů v České republice. Systém pro vizualizaci onkologických dat. Dostupné z WWW: <http://www.svod.cz>.

3. Nucci MR, Crum CHP. Redefining early cervical neoplasia: recent progress. Adv Anat Pathol 2007; 14(1): 1–10.

4. Bekker-Grob EW, de Kok IM, Bulten J et al. Liquid-based cervical cytology using ThinPrep technology: weighing the pros and cons in a cost-effectiveness analysis. Cancer Causes Control 2012; 23(8): 1323–1331.

5. Meijer CJ, Berkhof J, Castle PE, et al. Guidelines for human papillomavirus DNA test requirements for primary cervical cancer screening in women 30 years and older. Int J Cancer 2009; 124 (3): 516–520.

6. Schiffman M, Clifford G, Buonaguro FM. Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline. Infect Agent Cancer 2009; 4: 8. Dostupné z DOI: <http://doi: 10.1186/1750–9378–4-8>.

7. Tachezy R, Smahelova J, Salakova M, et al. Human papillomavirus genotype distribution in Czech women and men with diseases etiologically linked to HPV. PLoS One 2011; 6(7): e21913. Dostupné z DOI: <http://doi: 10.1371/journal.pone.0021913>.

8. Szarewski A, Mesher D, Cadman L et al. Comparison of seven tests for high-grade cervical intraepithelial neoplasia in women with abnormal smears: the Predictors 2 study. J Clin Microbiol 2012; 50 (6): 1867–1873.

9. Hublarová P, Hrstka R, Rotterová P et al. Prediction of human papillomavirus 16 e6 gene expression and cervical intraepithelial neoplasia progression by methylation status. Int J Gynecol Cancer 2009; 19(3): 321–325.

10. Yim EK, Park JS. Biomarkers in cervical cancer. Biomark Insights 2006; 2: 215–225.

11. Pluta M. Konsensus pro řešení abnormálních nálezů ve screeningu cervikálních karcinomů. Gynekologie po promoci 2009; 9(2): 53.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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