#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Stolz A., Šimonek J., Haruštiak T., Schützner J., Pafko P., Lischke R.: Timeline Trends in Surgery of Bronchogenic Carcinoma


Authors: A. Stolz;  J. Šimonek;  T. Haruštiak;  J. Schützner;  P. Pafko;  R. Lischke
Authors‘ workplace: III. chirurgická klinika 1. LF UK a FN Motol, Praha, přednosta: MUDr. R. Lischke
Published in: Rozhl. Chir., 2011, roč. 90, č. 4, s. 216-221.
Category: Monothematic special - Original

Overview

Background:
The aim of our study was to determine how patient preoperative status and outcomes of resection have changed over last 12 years.

Material and Methods:
This retrospective study of prospective database included 1412 patients operated from January 1, 1998 through December 31, 2009. Patient characteristics and outcomes were compared for two time periods (1998–2003 and 2004–2009).

Results:
We performed 985 lobectomies with 30-days mortality 1.8% and 300 pneumonectomies with 30-days mortality 5.7%. Median of survival of all 1412 patients was 4.3 year and 5-year survival was 45%. The percentage of female patients, lobectomies and adenocarcinoma increased over time, as well as age of our patients. Outcome improved over time, with significant decrease in 30-days mortality after pneumonectomy (8.2% vs. 2.3%, p = 0.029). The overall 3-year survival improved in patients with III. stage (30 % vs. 40 %, p = 0.012).

Conclusion:
Our study identified time trends which are in-line with increased incidence of lung cancer among women and with improvement of preoperative evaluation, preoperative and postoperative care

Key words:
lung cancer – resection – mortality


Sources

1. Watanabe, S., Asamura, H., Suzuki, K., Tsuchiya, R. Recent results of postoperative mortality for surgical resections in lung cancer. Ann. Thorac. Surg., 2004; 78: 999–1002.

2. Ferguson, M. K., Vigneswaran, W. T. Changes in patient presentation and outcomes for major lung resection over three decades. Eur. J. Cardiothorac. Surg., 2008; 33: 497–501.

3. de Perrot, M., Licker, M., Bouchardy, C., et al. Sex differences in presentation, management, and prognosis of patients with non-small cell lung carcinoma. J. Thorac. Cardiovasc. Surg., 2000; 119: 21–26.

4. Little, A. G., Rusch, V. W., Bonner, J. A., et al. Patterns of surgical care of lung cancer patients. Ann. Thorac. Surg., 2005; 80: 2051–2056.

5. de Perrot, M., Licker, M., Reymond, M. A., et al. Influence of age on operative mortality and long-term survival after lung resection for bronchogenic carcinoma. Eur. Respir. J., 1999; 14: 419–422.

6. Cerfolio, R. J., Bryant, A. S. Survival and outcomes of pulmonary resection for non-small cell lung cancer in the elderly: a nested case-control study. Ann. Thorac. Surg., 2006; 82: 424–429.

7. Marel, M., Mericka, O., Stránská, P., et al. Operabilita bronchogenního karcinomu – historie a současnost. Cas. Lek. Cesk., 2005; 144: 670–673.

8. Thomas, P., Doddoli, C., Thirion, X., et al. Stage I non-small cell lung cancer: a pragmatic approach to prognosis after complete resection. Ann. Thorac. Surg., 2002; 73: 1065–1070.

9. Yamamoto, K., Ohsumi, A., Kojima, F., et al. Long-term survival after video-assisted thoracic surgery lobectomy for primary lung cancer. Ann. Thorac. Surg., 2010; 89: 353–359.

10. Okada, M., Nishio, W., Sakamoto, T., et al. Long-term survival and prognostic factors of five-year survivors with complete resection of non-small cell lung carcinoma. J. Thorac. Cardiovasc. Surg., 2003; 126: 558–562.

11. Cerfolio, R. J., Bryant, A. S., Scott, E., et al. Women with pathologic stage I, II, and III non-small cell lung cancer have better survival than men. Chest, 2006; 130: 1796–1802.

12. Rami-Porta, R., Tsuboi, M. Sublobar resection for lung cancer. Eur. Respir. J., 2009; 33: 426–435.

13. Tamura, M., Hoda, M. A., Klepetko, W. Current treatment paradigms of superior sulcus tumours. Eur. J. Cardiothorac. Surg., 2009; 36: 747–753.

14. Caglar, H. B., Baldini, E. H., Othus, M., et al. Outcomes of patients with stage III nonsmall cell lung cancer treated with chemotherapy and radiation with and without surgery. Cancer, 2009; 115: 4156–4166.

15. Weder, W., Collaud, S., Eberhardt, W. E., et al. Pneumonectomy is a valuable treatment option after neoadjuvant therapy for stage III non-small-cell lung cancer. J. Thorac. Cardiovasc. Surg., 2010; 139: 1424–1430.

Labels
Surgery Orthopaedics Trauma surgery

Article was published in

Perspectives in Surgery

Issue 4

2011 Issue 4

Most read in this issue
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#