#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Accuracy of Preoperative Establishment of Invasive Breast Carcinoma Size Using Ultrasound and Mammography


Authors: P. Vrtělová;  O. Coufal;  V. Fait;  V. Chrenko
Authors‘ workplace: Oddělení chirurgické onkologie, Masarykův onkologický ústav Brno
Published in: Rozhl. Chir., 2010, roč. 89, č. 10, s. 599-603.
Category: Monothematic special - Original

Overview

Introduction:
Accurate preoperative assessment of breast cancer size is important for choosing appropriate surgical treatment. Mammography and ultrasonography are the most widely used breast imaging techniques. The aim of this study was to compare the tumour size measured by these two modalities with the pathological size of native specimen.

Methods and Subjects:
From 2001 to 2007, a retrospective review was conducted of 299 patients operated on at Masaryk Memorial Cancer Institute for the diagnosis of invasive breast carcinoma detected on ultrasonography or mammography as a nucleus shadow lesion where the preoperative size was estimated. Pearson’s correlation to pathological size was tested and the mean deviation was analysed in the whole group of patients as well as in subgroups defined by pathological size (pT), histogical type and grading.

Results:
Utrasonography was accurate in determination of the tumour size (i.e. within the deviation of 5mm) in 195 patients (74%), it underestimated in 45 cases (17%) and overestimated in 24 cases (9%). Pearson’s correlation coefficient (r) was 0.610 and mean deviation minus 0.115 cm. Mammography estimated accurate results in 162 patients (81%), the size was underestimated in 14 cases (7%) and overestimated in 25 (12%). Pearson’s correlation coefficient (r) was 0,645 and mean deviation 0.08 cm. Generally lower accuracy in assessing the size was noted in lobular carcinomas.

Conclusions:
Despite some limitations of our study, we can resume that in most cases (approximately 75%) the size assesement of invasive tumour lesion by both ultrasound and mammography is relatively reliable within the deviation of 5mm from the pathological size. But there’s still been some portion of cases remaining where the estimation is not accurate, therefore we are not completely able to avoid redundant removal of tissue or, on contrary, demand of consecutive operations due to positive resection margins.

Key words:
breast carcinoma – size – ultrasonography – mammography – partial mastectomy – total mastectomy – surgical treatment


Sources

1. Coufal, O., Fait, V., Foltinová, V. Chirurgická léčba karcinomu prsu v MOÚ. Rozhl. Chir., 2007 Oct; 86(10): 540–547.

2. Fait, V., Coufal, O., Gatěk, J. Chirurgie karcinomu prsu v České republice. Klin Onkol., 2009; 22(6): 294–295.

3. Svobodník, A., Daneš, J., Skovajsová, M., et al. Akutní stav národního programu skríninku rakoviny prsu v České republice. Cas. Lek. Cesk., 2007; 146(12): 945–949.

4. Heusinger, K., Lohberg, C., Lux, M. P., et al. Assessment of breast cancer tumor size depends on method, histopathology and tumor size itself. Breast Cancer Res. Treat., 2005 Nov; 94(1): 17–23.

5. Shoma, A., Moutamed, A., Ameen, M., et al. Ultrasound for accurate measurement of invasive breast cancer tumor size. Breast J., 2006 May-Jun; 12(3): 252–256.

6. Yang, W. T., Lam, W. W., Cheung, H. S., et al. Sonographic, magnetic resonance imaging, and mammographic assessments of preoperative size of breast cancer. J. Ultrasound Med., 1997 Dec; 16(12): 791–797.

7. Davis, P. L., Staiger, M. J., Hartus, K. B., et al. Breast cancer measurements with magnetic resonance imaging, ultrasonography, and mammography. Breast Cancer Res. Treat., 1996, 37: 1–9.

8. Mann, R. M. The effectiveness of MR imaging in the assessment of invasive lobular carcinoma of the breast. Magn. Reson. Imaging Clin. N. Am., 2010 May; 18(2): 259–276.

9. Flanagan, F. L., McDermott, M. B., Barton, P. T., et al. Invasive breast cancer: mammographic measurement. Radiology, 1996 Jun; 199(3): 819–823.

10. Hieken, T. J., Harrison, J., Herreros, J., et al. Correlating sonography, mammography and pathology in the assessment of breast cancer size. Am. J. Surg., 2001 Oct; 182(4): 351–354.

11. Bosch, A. M., Kessels, A. G., Beets, G. L., et al. Preoperative estimation of the pathological breast tumour size by physical examination, mammography and ultrasound: a prospective study on 105 invasive tumours. Eur. J. Radiol., 2003 Dec; 48(3): 285–292.

Labels
Surgery Orthopaedics Trauma surgery
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#