The contribution of nuclear medicine in the diagnosis and therapy of the patient with peritoneal strumosis – case report
Authors:
D. Chroustová 1; K. Žabková 2; V. Ptáčník 1; L. Planičková 3; K. Táborská 4; P. Vlček 4
Authors‘ workplace:
Ústav nukleární medicíny
1; 3. interní klinika
2; Ústav patologie 1. LF UK a VFN Praha
3; Klinika nukleární medicíny a endokrinologie, 2. LF UK a FN Motol Praha, ČR
4
Published in:
NuklMed 2025;14:34-38
Category:
Casuistry
Overview
Ovarian struma is a rare tumour classified as an ovarian teratoma. Most metastatic ovarian strumas consist of papillary or follicular carcinoma. We present a unique case of the patient with ovarian struma and peritoneal strumosis. The 58-year-old woman was followed up with the symptomatic hyperthyroidism of unclear aetiology, which persisted even after total thyroidectomy. Following a series of the imaging studies and a lymph node biopsy, a well-differentiated follicular carcinoma was identified, arising from additionally detected ovarian struma. Whole-body scintigraphy using 99mTc-sodium pertechnetate detected multiple radiopharmaceutical foci in the abdominal cavity, corresponding to the thyroid tissue supporting the suspected ovarian struma. The patient underwent debulking surgery with hysterectomy and bilateral adnexectomy and further extirpation of tumorous foci in the abdominal cavity. Histological examination confirmed dissemination of well-differentiated follicular neoplasm with a follicular variant of the papillary thyroid carcinoma. 131I therapy was performed, followed by diagnostic and post-therapeutic scintigraphy using 131I.
Keywords:
peritoneal strumosis – 99mTc-TO4 SPECT/low dose CT – radioiodine therapy and monitoring
Sources
- Gruhn J. A selective historical survey of ovarian pathology emphasizing neoplasms in Roth I.M. Czernobilsky B, editors. Tumors and tumor like conditions of the ovary vol 6, New York: Churchill Livingstone 1985, p.269-285
- Roth IM, Telerman A. Recent edvances the pathology and classification of ovarian germ cell tumors. Int J Gynecol Pathol 2006; 25 : 305-320
- Kaleem T, Peterson J, Krishna M. Peritoneal strumosis: Presentation and management with multiple radioactive indine treatments. Journal of Clinical and Translational Endocrinology: Case reports; 2018; 8 : 1-4. doi.org/10.1016/j.jecr.2018.01.002
- Roth IM, Telerman A. The enigma of struma ovarii. Pathology 2007; 39 : 139-146
- Garg K, Soslow RA, Rivera M et al: Histologically bland extremely welldifferenciated thyroid carcinoma sarising in struma ovarii canrecur and metastazice. Int J Gynecol Pathol 2009; 28 : 222-230
- Koo PJ, Klingensmith WC 3rd, Bagrosky BM, Haugen BR. SPECT/CT of metastatic struma ovarii. Clin Nucl Med 2014; 39 : 186-187
- Young RH, Jackson A, Wells M. Ovaria nmetastasis from thyroid carcinoma 12 years after partial thyroidectomy mimicking struma ovarii: report of a case. Int J Gynecol Pathol 1994; 13 : 181-185
- Checrallah A, Medlej R, Saade C et al. Malignant struma ovarii: an unusual presentation. Thyroid 2001; 11 : 889-892
- Groener D, Baumgarten J, Happel Ch et al. Thyroid papillary cancer elements arising from struma ovarii with bening peritoneal strumosis: Utility of iodine -123-imaging in diagnostics and treatment planning. Clin Case Rep 2023; 11: e07311
Labels
Nuclear medicine Radiodiagnostics RadiotherapyArticle was published in
Nuclear Medicine

2025 Issue 3
Most read in this issue
- S1 Abstrakta – 61. DNM, Liberec 24. – 26. září 2025
- The contribution of nuclear medicine in the diagnosis and therapy of the patient with peritoneal strumosis – case report
- Noví členové společnosti
- S2 Abstrakta – XLVI. Pracovní dny radiofarmaceutické sekce ČSNM, Olomouc 28. – 30. května 2025