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Importance of breath tests for the evaluation liver function in patients with chronic kidney disease
Authors: Nikola Mejzlíková 1; Karolína Krátká 1; Miluše Vejvodová 1; Pavla Libicherová 1; Nikola Uzlová 1; Jana Vránová 2; Ivan Rychlík 1
Authors‘ workplace: I. interní klinika 3. LF UK a FN Královské Vinohrady, Praha 1; Ústav lékařské biofyziky a lékařské informatiky 3. LF UK Praha 2
Published in: Vnitř Lék 2020; 66(3): 50-52
Category:
Overview
Breath tests for the evaluation liver metabolic function are a non-invasive diagnostic method with high sensitivity and specificity. Up today, the issue of liver damage in patients with chronic kidney disease has not been investigated sufficiently, although it might have significant clinical consequences. The following article describes the principles of breath tests, experiences with breath tests in patients with chronic kidney disease (CKD) and the results of our pilot study with methacetin breath tests in patients with CKD and in regular peritoneal dialysis treatment.
Keywords:
13C‑methacetin breath test – chronic kidney disease – kidney‑liver organ cross talk – metabolic liver function
Sources
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2. Matsumoto K, Suehiro M, Iio M, et al. 13C)methacetin breath test for evaluation of liver damage. Dig Dis Sci 1987; 32 : 344–348.
3. Leblond F, Giroux L, Villeneuve JP, et al. Decreased in vivo metabolism of drugs in chronic renal failure. Drug Metab Dispos 2000; 28 : 1317–1320.
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Labels
Diabetology Endocrinology Internal medicine
Article was published inInternal Medicine
2020 Issue 3-
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