Obesity and cardiovascular disease

Czech version

Authors: Štěpán Svačina
Authors‘ workplace: III. interní klinika UK – 1. LF a VFN Praha
Published in: Vnitř Lék 2020; 66(2): 89-91
Category: Main Topic

Overview

Obesity with no comorbidities probably carries no cardiovascular risk, and the so-called obesity paradox even comes into play, wherein obesity may improve the prognosis of cardiovascular disease. Cardiovascular complications primarily occur indirectly due to metabolic comorbidities of obesity. However, a thrombogenic potential of obesity has also been established. A very important question in contemporary obesitology is whether antidiabetics currently administered in obese non-diabetic individuals will have a positive cardiovascular effect similar to that in diabetics. Myokines, muscle tissue hormones, certainly have a protective effect on the cardiovascular system. Also of importance is the research into epicardial and pericardial fat. Its investigation and management will aid in finding additional options of diagnosing and treating cardiovascular disease.

Keywords:

antidiabetics – obesity paradox – cardiovascular risk – obesity complications – antiobesity drugs – epicardial fat – pericardial fat

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