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Internal medicine and cognitive decline in seniors


Authors: H. Matějovská Kubešová;  H. Meluzínová;  P. Weber
Authors‘ workplace: Klinika interní, geriatrie a praktického lékařství Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednostka prof. MUDr. Hana Matějovská Kubešová, CSc.
Published in: Vnitř Lék 2011; 57(5): 502-506
Category: Reviews

Overview

Authors show the situation in diagnostics and treatment of cognitive deterioration in elderly. There are stressed chronic diseases influencing significantly influencing the development of dementia. Adequate treatment of these diseases was proved as a factor delaying the cognitive decline. The relationship between different groups of medications and cognitive performance are discussed. The importance of nutrition of elderly and possible microelements deficits are mentioned – specially group B vitamines, polyunsaturated fatty acids etc. Special part of the article show the importance of physical and psychical activities from the cognition point of view. Depression is discussed as a potentiating factor of dementia development. The table of recommendations to preventive, prophylactical and diagnostic measures how to improve the management of cognitive deterioration in elderly.

Key words:
cognitive functions – dementia – early diagnostics – secondary dementia – nutrition in elderly – depression


Sources

1. Barnes DE, Yaffe K. Predicting dementia: role of dementia risk indices. Future Neurol 2009; 4: 555–560.

2. Desai AK, Grossberg GT, Chibnall JT. Healthy brain aging: a road map. Clin Ge­riatr Med 2010; 26: 1–16.

3. Mihaescu R, Detman SB, Cornel MC et al. Translational Research in Genomics of Alzheimer’s Disease: A Review of Current Practice and Future Perspectives. J Alz­heimers Dis 2010; 4: 976–980.

4. Duron E, Hanon O. Antihypertensive treatments, cognitive decline and dementia. J Alzheimer Dis 2010; 3: 903–914.

5. Češka R, Krutská S, Zlatohlávek L et al. Komplexní léčba kardiovaskulárního rizika. Zaměřeno na telmisartan. Vnitř Lék 2010; 56: 839–844.

6. Li NC, Lee A, Whitmer RA et al. Use of angiotensin receptor blockers and risk of dementia in predominantly male population: prospective cohort analysis. BMJ 2010; 340: b5465 doi: 10.1136.

7. Widimský J. Cílové hodnoty léčby hypertenze. Budou platit i u starších hypertoniků, diabetiků a pacientů s ICHS? Vnitř Lék 2009; 55: 833–840.

8. Cole GM, Frautschy SA. Mechanisms of action of non-steroidal anti-inflamatory drugs for the prevention of Alzhei­mer’s Disease. CNS Neurol Disord Drug Targets 2010; 2: 140–148.

9. Eskelinen MH, Kivipelto M. Caffeine as a protective factor in dementia and Alzhei­mer’s disease. J Alzheimer’s Dis 2009; 1: 85–91.

10. Etgen T, Bickel H, Förstl H. Metabolic and endocrine factors in mild cognitive impairment. Ageing Res Rev 2010; 3: 280–288.

11. Morley JE. Nutrition and the brain. Clin Geriatri Med 2010; 26: 89–98.

12. Cole GM, Frautschy SA. DHA may prevent age-related dementia. J Nutr 2010; 140: 869–874.

13. Carrié I, Abellan Van Kan G, Rolland Y. PUFA for prevention and treatment of dementia. Cur Pharm Des 2009; 15: 4173–4185.

14. Oudshoom C, Matace-Raso FU, ven der Velde M et al. Higher serum vitamin D3 levels are associated with better cognitive test performance in patients with Alzheimer’s disease. Dement Geriatr Cog Disord 2008; 25: 839–843.

15. Gezen-Ak D, Dursun E, Ertan T et al. Association between vitamin D receptor gene polymorfism and Alzheimer’s disease. Tohoku J Exp Med 2007; 212: 275–282.

16. Bartolomeyczik S, Reuther S, Luft L et al. Prevalence of Malnutrition, Interventions and Quality Indicators in German Nursing Homes – first results of a nationwide pilot study. Gesundheitswesen 2010; 72: 868–874.

17. Etgen T, Sander D, Huntgeburth U et al. Physical activity and incident cognitive impairment in elderly persons: study INVADE. Arch Intern Med 2010; 170: 186–193.

18. Rolland Y, Abellan van Kan G, Vellas B. Healthy brain ageing – role of exercise and physical activity. Clin Geriatr Med 2010; 26: 75–87.

19. Baker LD, Frank LL, Foster-Schubert K et al. Effects of aerobic exercise on mild cognitive impairment: a controlled trial. Arch Neurol 2010; 67: 71–79.

20. Kroner Z. The relationship between Alzheimer’s disease and diabetes: Type 3 diabetes? Altern Med Rev 2010; 14: 373–379.

21. Scherder E, Eggermont L, Achtenberg W et al. Pain and physical (in)activity in relation to cognition and behavior in dementia. Tijdschr Gerontol Geriatr 2009; 40: 270–278.

22. Taniguchij Y, Kousa Y, Shinkai S et al. Increased physical and intellectual activity and changes in cognitive functions in elderly dwellers: lessons from the community-based dementia prevention trial in Suginami ward. Nippon Koshu Eisei Zashi 2009; 56: 784–794.

23. Mowszowski L, Batchelor J, Naismith JL. Early intervention for cognitive decline: can cognitive training be used as a selective prevention technique? Int Psychogeriatr 2010; 22: 537–548.

24. Reisberg B, Shulman MB, Torossian C. Outcome over seven years of healthy adults with and without subjective cognitive impairment. Alzheimers Dement 2010; 6: 11–24.

25. Espino DV, Jules-Bradley AC, Johnston CL. Diagnostic approach to the confused el­derly patient. Am Fam Physician 1998; 57: 1358–1366.

26. Pisani MA, Kong SY, Kasl SV et al. Days of Delirium are Associated with 1-year Mortality in an Older Intensive Care Unit Population. J Fam Pract 2009; 58: E1.

27. Matejovsky J, Kubesova H, Meluzinova H et al. Depression in elderly do we consider it enough? World Congress of Wonca Singapure 2007, Proceedings p. 600.

28. Bellelli G, Frisoni GB, Turco R et al. Depressive symptoms combined with dementia affect 12-months survival in elderly patients after rehabilitation post-hip fracture surgery. Int J Geriat Psychiatry 2008; 10: 1073–1077.

29. Most EI, Scheltens E, van Someren EJ. Prevention of depression and sleep disturbances in elderly with memory problems by activation of biological clock with light – a randomized clinical trial. Trials 2010; 11: 19.

Labels
Diabetology Endocrinology Internal medicine
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