#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Autoimmune thyropathies in diabetics


Authors: Z. Schroner 1;  I. Lazúrová 2;  J. Petrovičová 3
Authors‘ workplace: NZZ interná a diabetologická ambulancia, Moldava nad Bodvou, Slovenská republika 1;  I. interná klinika Lekárskej fakulty Univerzity P. J. Šafárika a FN, Košice, Slovenská republika, prednostka prof. MUDr. Ivica Lazúrová, CSc. 2;  Ústav lekárskej informatiky Lekárskej fakulty Univerzity P. J. Šafárika a FN, Košice, Slovenská republika, prednostka RNDr. Jozefína Petrovičová 3
Published in: Vnitř Lék 2006; 52(2): 137-143
Category: Original Contributions

Overview

Autoimmune thyropathies are frequent in patients with type 1 diabetes mellitus. Some recently published papers confirm similarly high prevalence of autoimmune thyropathies also in patients with type 2 diabetes mellitus. Chronic autoimmune thyroiditis is the most frequent form of autoimmune thyropathies. Authors examined 79 accidentally selected diabetics (38 women and 41 men, x = 55.4 ± 2.8). Diabetic patients were divided into three groups. 20 patients with type 1 diabetes mellitus - classical form were the first group, 12 patients with LADA were the second group and 47 patients with type 2 diabetes mellitus constituted the third group. Authors diagnosed chronic autoimmune thyroiditis in 8 (40 %) patients in the group of patients with type 1 diabetes mellitus, in 6 (50 %) in the group of patients with LADA and in 20 (43 %) of patients with type 2 diabetes mellitus. They didn`t find out statistically more frequent prevalence of chronic autoimmune thyroiditis in all groups of patients with diabetes (patients with type 1 diabetes mellitus, patients with LADA, patients with type 2 diabetes mellitus) in comparison with control group of non-diabetic subjects. They found out statistically significant more frequent prevalence of chronic autoimmune thyroiditis in diabetics of woman gender and in diabetics with positive family history of thyropathies. Results of paper confirm recommendation of examining once or twice a year autoantibodies against thyroid gland and level of thyrotropin (TSH) with the aim of early finding of laboratory manifestation of thyroidal autoimmunity or developing functional disorder.

Key words:
chronic autoimmune thyroiditis - diabetes mellitus type 1 - diabetes mellitus type 2


Sources

1. Zamrazil V, Vondra K. Štítná žľáza a diabetes. In: Bartoš V, Pelikánová T. Praktická diabetologie. 2. ed. Praha: Maxdorf 2000: 400-414.

2. Vondra K, Zamrazil V. Onemocnění štítné žlázy u dospělých diabetiku. In: Perušičová J Trendy soudobé diabetologie. Praha: Galén 2004: 31-48.

3. Kiňová S, Payer J, Kalafutová I et al. Výskyt autoimunitnej tyreopatie u pacientov s diabetes mellitus 1. typu. Bratis Lek Listy 1998; 99: 23-25.

4. Krejči H, Perušičová J. Autoimunitní tyreopatie u diabetes mellitus 1. a 2. typu. DMEV 2004; 7: Abstr. 164.

5. Matějková-Běhanová M, Kvíčala J, Čeřovská J et al. Výskyt autoimunitní tyreoiditidy u diabetiku středního a staršího věku: srovnání s nediabetiky. DMEV 2004; 7(Suppl.1): 33.

6. Holl RW, Bohm B, Loos U et al. Thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus. Effect of age, gender, and HLA type. Horm Res 1999; 52: 113-118.

7. Roldan MB, Alonso M, Barrio R. Thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus. Diabetes Nutr Metab 1999; 12: 27-31.

8. Vondra K, Zamrazil V. Onemocnění štítné žlázy u nemocných s diabetes mellitus. DMEV 2002; 5: 78-84.

9. Groop L, Miettinen A, Groop PH et al. Organ-specific autoimmunity and HLA-DR antigens as markers for beta-cell destruction in patients with type II diabetes. Diabetes 1988; 37: 99-103.

10. Běhanová-Matějková M, Zamrazil V, Vondra K et al. Middle-aged onset type 1 diabetes: Differences among individuals with and without autoimmune thyroiditis. Diabetologia 2000; 43(Suppl 1): A110.

11. Vanderpump MPJ, Tundbridge WMG. The epidemiology of autoimmune thyroid disease. In: Volpe R et al. Contemporary endocrinology: Autoimmune endocrinopathies. Human Pres Inc 1999: 141-162.

12. Límanová Z, Jiskra J. Autoimunitní tyreopatie - královna endokrinních syndromů. DMEV 2004; 7(Suppl 2): 32-35.

13. Hak AE, Pols HAP et al. Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: The Rotterdam Study. Ann Int Med 2000; 132: 270-278.

Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 2

2006 Issue 2

Most read in this issue
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#