The Relation of some Posttranslational Modifications of Proteins of HumanTissues to the Age and their Application for Age Estimation in ForensicMedicine. A Review of Knowledge


Authors: A. Pilin 1;  F. Pudil 2;  J. Sajdok 3;  J. Zídková 4;  D. Bezdíčková 5;  V. Bencko 6
Authors‘ workplace: Ústav soudního lékařství a toxikologie 1. LF UK a VFN, Praha 2Ústav chemie a analýzy potravin Fakulty potravinářské a biochemické technologieVŠCHT, Praha3Ústav biochemie a mikrobiologie Fakulty potravinářské a biochemické technologie VŠCHT, Praha4Ústav bi 1
Published in: Soud Lék., , 2003, No. 4, p. 54-56
Category:

Overview

This article deals with some of posttranslational modifications of proteins which are, or could beuseful to work out objective and standard methods for age estimation in forensic medicine. Frommany posttranslational modifications other than racemization, the evaluation of pentosidine, oneof the products of nonenzymatic glycosylation, seems to be promising. The enlargement of menuof methods for age estimation is important mainly for forensic sciences when determination ofthe age of an unknown dead body is necessary. Morphological methods are quite often subjectiveand charged with errors.

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Labels
Anatomical pathology Forensic medical examiner Toxicology
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