Authors: P. Křížová 1; B. Kříž 2,3; Účastníci Prospektivní Studie 4 Authors‘ workplace: Národní referenční laboratoř pro meningokokové nákazy, Státní zdravotní ústav, Praha 2 Centrum epidemiologie a mikrobiologie, Státní zdravotní ústav, Praha 3 Oddělení epidemiologie, Centrum preventivního lékařství, 3. lékařská fakulta Univerzity Karlovy, Published in: Epidemiol. Mikrobiol. Imunol. , 1999, č. 4, s. 140-152 Category:
The nationwide prospective questionnaire study of cases and controls was implemented during theperiod from October 1996 till May 1998. Thirty-nine districts participated (=54.2% of district hygienestations) and 107 invasive meningococcal diseases were included in the study (=76.9% of diseasesrecorded during the given period in the Czech Republic by active surveillance). A total of 390subjects were included in the study – 107 with invasive meningococcal diseases, 211 healthy controlsand 72 healthy carriers of Neisseria meningitidis. This is the first study in the Czech Republic whichanalyzes comprehensively socioeconomic, health and stress factors in relation to the genesis anddevelopment of invasive meningococcal disease or carriership of N. meningitidis. The relationshipbetween these factors and meningococcal disease or carriership was evaluated by the chi squaretest: odds ratio (OR) and statistical significance (p for chi square – Yates correction or Fischer’sexact test). For the development of invasive meningococcal disease in particular, risk factors aresignificant (p
Key words: invasive meningococcal disease – carriership of Neisseria meningitidis – risk factors.
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