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Lymphocytic Myocarditis –⁠ A New Histopathological Definition and Classification for Endomyocardial Biopsies, Surgical and Autopsy Specimens (“Seaport Criteria”)


Authors: Václav Stejskal;  Jakub Šagát;  Tereza Sokolová
Authors‘ workplace: Fingerlandův ústav patologie, Fakultní nemocnice Hradec Králové a Univerzita Karlova, Lékařská fakulta v Hradci Králové
Published in: Čes.-slov. Patol., 62, 2026, No. 2, p. 120-124
Category: Reviews Article

Overview

Lymphocytic myocarditis is the most common form of inflammatory myocardial disease. However, its histopathological diagnosis has been burdened by considerable subjectivity until recently. In 2025, the Society for Cardiovascular Pathology (SCVP) and the Association for European Cardiovascular Pathology (AECVP) published a two-part document entitled the “Seaport Criteria,” which introduces new diagnostic approaches for endomyocardial biopsies and nonbiopsy specimens –⁠ surgical and autopsy material. This article summarizes the key elements of these documents, including practical recommendations for routine histopathological diagnosis.

Keywords:

endomyocardial biopsy – histopathology – lymphocytic myocarditis – lymphocyte cluster


Sources

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Labels
Anatomical pathology Forensic medical examiner Toxicology

Article was published in

Czecho-Slovak Pathology

Issue 2

2026 Issue 2

Most read in this issue
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