Nerve Sheath Myxoma with Bidirectional Schwannomatous and Perineural Differentiation
Authors:
M. Zámečník; T. Sedláček
Authors‘ workplace:
Medicyt, s. r. o., laboratory Trenčín, Slovak Republic
Published in:
Čes.-slov. Patol., 46, 2010, No. 3, p. 73-76
Category:
Overview
Prezentovaný je prípad myxómu nervového púzdra u 70-ročnej pacientky v okcipitálnej oblasti. Tumor mal typickú lobulárnu a myxoidnú morfológiu tejto zriedkavej jednotky. Neobvyklá bola difúzna koexpresia markerov Schwannových buniek S100 proteinu a GFAP a perineurálnych markerov EMA a claudin-1. CD34+ fibroblastické bunky boli málo početné a nervové axóny neboli v tumore nájdené. Diskutovaná je klinická patológia a histogenéza lézie.
Kľúčové slová:
myxóm nervového púzdra – perineurióm – schwannóm – epitelový membránový antigén – S100 protein
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