Authors: V. Ciprová 1; C. Povýšil 1; D. Dudorkinová 1; L. Šafařík 2; T. Zelinka 3 Authors‘ workplace: Ústav patologie 1. LF UK a VFN, Praha 2Urologická klinika 1. LF UK a VFN, Praha3III. interní klinika 1. LF UK a VFN, Praha 1 Published in: Čes.-slov. Patol., , 2004, No. 3, p. 102-105 Category:
Oncocytic neoplasms of the adrenal gland are rare, as described in literature. Only 27 cases havebeen reported up to now in world literature. Here we describe our experience. In this report wediscuss the clinicopathologic and immunohistochemical findings of three oncocytic tumors of theadrenal cortex. Two tumors were found during examination of the patients for other reasons.These tumors were hormonally inactive. One tumor manifested by the virilization of the patient.Immunohistochemical examination demonstrated in all tumors focal positivity with antibodies toneuron-specific enolase and synaptophysin and mostly focally weak positivity for cytokeratins.Very low mitotic activity was found in two tumors. Criteria for evaluation of biological characterof this type of tumors are not established.
Key words: adrenals – adrenal cortex – oncocytoma – malignancy
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