Histological findings in a completely duplicated kidney and ureter after heminephrectomy
Authors:
Martina Košudová 1; Minh Nguyet Tranová 2; Pavel Navrátil 2,3; Miroslav Podhola 4; Ivo Novák 2
Authors‘ workplace:
Urologie, Nemocnice Havířov
1; Urologická klinika, FN Hradec Králové
2; LF UK, FN Hradec Králové
3; Fingerlandův ústav patologie, FN Hradec Králové
4
Published in:
Ces Urol 2025; 29(3): 164-169
Category:
Original article
doi:
https://doi.org/10.48095/cccu2025018
Overview
Introduction: Complete duplication of the kidney and ureter is a common congenital anomaly of the urinary tract, often associated with ectopic ureter, ureterocele, or vesicoureteral reflux. In cases of severe hypofunction of the upper moiety, heminephrectomy is indicated. Objective: The aim of this study was to analyze the histopathological findings in resected upper segments of completely duplicated kidneys in pediatric patients undergoing heminephrectomy. Methods: A retrospective analysis was conducted on 26 children operated on between 2000 and 2024 for complete duplication of the upper urinary tract at the University Hospital Hradec Králové. Clinical data and histological findings were evaluated. Results: The most frequent findings were chronic inflammatory changes (77%) and renal dysplasia (46%), more commonly associated with ectopic ureter than ureterocele. Additional findings included tubular atrophy, interstitial fibrosis, glomerulosclerosis, and urothelial metaplasia in one case. Conclusion: Histopathological changes in the upper moiety of completely duplicated kidneys reflect a combination of congenital and secondary damage, resulting in irreversible loss of segmental function. Heminephrectomy is an effective therapeutic method, and histological analysis contributes to a better understanding of the pathogenesis of these conditions.
Keywords:
pediatric urology – heminephrectomy – histopathology – duplicated kidney
Sources
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Labels
Paediatric urologist Nephrology UrologyArticle was published in
Czech Urology
2025 Issue 3
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