48 years of interventional treatment of cardiovascular diseases at the Children’s Heart Centre
Authors:
Václav Chaloupecký
Published in:
Čes-slov Pediat 2025; 80 (3): 127-131.
Category:
Review
doi:
https://doi.org/10.55095/CSPediatrie2025/014
Overview
Chaloupecký V. 48 years of interventional treatment of cardiovascular diseases at the Children’s Heart Centre
This review article summarizes the early and long-term results of interventional treatment of congenital heart disease (CHD) at the Children’s Heart Centre. Between 1977 and 2024, a total of 7,027 interventional cardiac catheterizations and 17,182 cardiac surgeries, including 43 heart transplants, were performed in 19,120 individuals, of whom 17,323 (90.6%) had congenital heart disease and 1,797 (9.4%) had primary dysrhythmias and/or acquired heart disease. Early postoperative mortality has been around 1% over the last 20 years.
Long-term prognosis was evaluated in 13,348 children with CHD born between 1978 and 2020, who underwent a total of 14,408 cardiac surgeries and 4,565 interventional cardiac catheterizations during the same time period. The probability of survival at 10, 20, 30 and 40 years after the first intervention was 84.8%, 82.5%, 79.4% and 77.7% in the group of 4,419 individuals with complex CHD and 96.2%, 95.1%, 93.9% and 91.9% in the group of 8,929 individuals with other CHD (HR 3.8: CI 3.4 4.3; p < 0.001). At the end of year 2020, a total of 5,915 children and 6,263 adults were alive after cardiovascular intervention at the Children’s Heart Centre, of whom 1,868 (31.6%) children and 1,796 (28.7%) adults had complex CHD.
Conclusion. In the population of the Czech Republic, the number of adults with complex congenital heart disease after cardiovascular interventions in childhood is increasing. Dispensing and follow-up of these individuals in specialized centers for adults with congenital heart disease are essential.
Keywords:
cardiac surgery – Congenital heart defects – interventional cardiac catheterization – long-term prognosis
Sources
1. Šamánek M, Voříšková M. Congenital heart disease among 815,569 children born between 1980 and 1990 and their 15-year survival: a prospective Bohemia survival study. Pediatr Cardiol 1999; 20(6): 411–417.
2. Šamánek M, Benešová D, Goetzová J, Hrycejová I. Distribution of age at death in children with congenital heart disease who died before the age of 15. Br Heart J 1988; 59: 581–585.
3. Hučín B, Žáček P. Dětská kardiochirurgie. Praha: Grada 2001.
4. Šamánek M, Voříšková M. Infants with critical heart disease in a territory with centralized care. Int J Cardiol 1987; 16: 75–91.
5. Hučín B, Fišer B, Kučera V, et al. Operace na otevřeném srdci u dětí v nejútlejším věku metodou cílené zástavy oběhu v hluboké hypotermii. Cas lek ces 1980; 119: 1265–1271.
6. Barratt-Boyes BG, Simpson MM, Neutze N. Intracardiac surgery in neonates and infants using deep hypothermia with surface cooling and limited cardiopulmonary bypass. Circulation 1971; 43–44(suppl 1): 1–25.
7. Chaloupecký V, Hučín B, Fišer B. Pooperační péče a léčba respirační insuficience u kojenců a malých dětí operovaných pro vrozenou srdeční vadu
v hluboké hypotermii s cílenou zástavou oběhu. Cs Pediat 1981; 36: 307–310.
8. Tax P, Reich O, Škovránek J, et al. Vývoj intervenčních katetrizačních technik v dětské kardiologii. Cs Pediat 1997; 52: 358–364.
9. Gebauer R, Chaloupecký V, Hučín B, et al. Survival and freedom from reinterventions in patients with repaired tetralogy of Fallot: up to 42-year follow-up of 917 patients. J Am Heart Assoc 2023: e024771.
10. Koubský K, Gebauer R, Tláskal T, et al. Long-term survival and freedom from coronary artery reintervention after arterial switch operation for transposition of the great arteries: a population-based nationwide study. J Am Heart Assoc 2021: e020479.
11. Erikssen G, Liestol K, Seem E, et al. Achievements in congenital heart defect surgery: a prospective, 40-year study of 7038 patients. Circulation 2015; 131: 337–346.
12. Larsen SH, Olsen M, Emmertsen K, Hjortdal VE. Interventional treatment of patients with congenital heart disease: nationwide Danish experience over 39 years. J Am Coll Cardiol 2017; 69(22): 2725–2732.
Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2025 Issue 3
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