Authors: V. Resl 1; P. Cetkovská 1; M. Leba 1; I. Rampl 2 Authors‘ workplace: Dermatovenerologická klinika LF UK v Plzni přednosta prof. MUDr. Vladimír Resl, CSc. 1; Fakulta elektroniky a komunikačních technologií Vysokého učení technického v Brně a Enjoy spol. s r. o. vedoucí doc. Ing. Ivan Rampl, CSc. 2 Published in: Čes-slov Derm, 81, 2006, No. 3, p. 169-173 Category: New drugs, cosmetics, devices
Our research includes the use of several biomedical engineering devices for objective evaluation of results. Our readers were already acquainted with some of them. Profilometry monitors and evaluate roughness of skin surface. With technical progress many different approaches were suggested: mechanical stylus profilometry, optical, interference approaches, microscopical, holographical, laser and photometrical transmission measurement with replica. Every approach has its advantages and disadvantages. Comparison of reliability, reproducibility and validity of data was performed. Modern devices provides two-dimensional (2D) and spatial (3D) evaluation. It is possible to assess many statistically estimated parameters. Methods were used in effect evaluation of e.g. retinoids, glucocorticosteroids, emollients in atopy evaluation, professional dermatoses etc.
Key words: profilometry – skin surface – skin roughness – skin topography – skin wrinkles – use of profilometry
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