Cutaneou vasculitis in SLE – to treat or not to treat?


Authors: M. Gregová
Authors‘ workplace: Revmatologický ústav Praha
Published in: Čes. Revmatol., 28, 2020, No. 2, p. 110-115.
Category: Case Report

Overview

Systemic lupus erythematosus (SLE) is a disease with large variability in clinical manifestations. In present work we describe case of a young woman with SLE with multiple skin vasculitic lesions. We show how difficult can the treatment of cutaneous vasculitis be. Skin lesions have often necrotic bed, that attenuates bacterial superinfection and the decision on systemic immunosuppressive treatment accompanies mayor dilemma. Combination immunosuppressive therapy is also hazardous due to possible serious adverse effects; the therapy may worsen
underlining hematologic abnormalities that often 
accompany SLE. Nevertheless vasculitis is manifesta-
tion of systemic disease activity and therefor only adequate therapy leads to resolution of cutaneous vasculitic lesion.

Keywords:

systemic lupus erythematosus – cutaneous vasculitis – leucopenia – cyclophosphamide


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Labels
Dermatology & STDs Paediatric rheumatology Rheumatology
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