Pachydermoperiostosis


Authors: J. Vachtenheim;  A. Houzarová
Authors‘ workplace: Revmatologická ordinace, interní oddělení, Krajská nemocnice, Jihlava
Published in: Čes. Revmatol., 16, 2008, No. 3, p. 124-127.
Category: Case Report

Overview

The present contribution describes a patient with pachydermoperiostosis, a rare disease associated with hyperperiostosis (occuring predominantly in long bones of forearms and shanks), and clubbing of the digits of the hands and feet. Patients frequently have arthralgia of both the small and large joints. The diagnosis is based on X-ray and clinical observations. Laboratory examination often shows unspecific changes such as elevated erythrocyte sedimentation and C-reactive protein level. Similar X-ray and clinical finding should be considered in the differential diagnosis, which include malignancies (most frequently lung and gastrointestinal cancer), but also, for instance, inherited heart defects. The disease can be diagnosed with the aid of X-ray and laboratory examination, however. We present a case report of our second patient with typical symptoms of this rare disease. Our first observation has been described as early as in 1960.

Key words:
pachydermoperiostosis, incidence, clinical picture


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Labels
Dermatology & STDs Paediatric rheumatology Rheumatology
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