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Coincidence of giant uterine myomatosis and detection of two advanced malignancies in 77-year-old female patient


Authors: K. Bláhová;  J. Presl;  D. Berezovskiy;  P. Vlasák;  J. Bouda;  J. Kosťun
Authors‘ workplace: Gynekologicko-porodnická klinika FN, Plzeň, přednosta doc. MUDr. Z. Novotný, CSc.
Published in: Ceska Gynekol 2020; 85(3): 187-192
Category: Case Report

Overview

Objective: Our aim is to emphasize the importance of patient participation in screening programs available in the Czech Republic and in preventive gynaecological examinations. As an example, we present a case report of a 77-year-old female patient with the accumulation of serious gynaecological diseases (extreme uterine myomatosis, breast cancer) and non-Hodgkin´s B-lymphoma.

Design: Case report.

Setting: Department of Obstetrics and Gynaecology, Faculty Hospital in Pilsen, Charles University Medical Faculty in Pilsen.

Case report: Our case report of a 77-year-old patient is a rare case of the simultaneous detection of giant uterine myomatosis causing voluminous ventral hernia, invasive ductal breast cancer, and non-Hodgkin´s B-lymphoma. The patient was not gynecologically examined for last 20 years and did not undergo any screening examinations. In the postoperative period, the patient was diagnosed with invasive ductal breast cancer and follicular lymphoma. All the diseases were diagnosed in advanced stage.

Conclusion: The occurrence of bulky fibroids is very rare in postmenopause. Long-term neglect of clinical symptoms and adverse health signals allows their gradual progression. Especially in older patients, other serious illnesses may complicate the situation.

Keywords:

giant uterine fibroid – ventral hernia – breast cancer – non-Hodgkin´s B-lymphoma


Sources

1. Baird, DD., Dunson, DB., Hill, MC., et al. High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence. Am J Obstet Gynecol, 2003,188(1), p. 100–107.

2. Bartos, V., Korec, P., Ficek, R. Giant uterine leiomyoma in a  young woman as an incidental finding after a  car accident: a case report. Acta Medica, 2018, 61(1), p. 29–32.

3. Courtin, E., Knapp, M. Social isolation, loneliness and health in old age: a scoping review. Health Soc Care Community, 2017, 25(3), p. 799–812.

4. Holdsworth-Carson, SJ., Zaitseva, M., Vollenhoven, BJ., et al. Clonality of smooth muscle and fibroblast cell populations isolated from human fibroid and myometrial tissues. Mol Hum Reprod, 2014, 20(3), p. 250–259.

5. Knuttel, FM., Menezes, GL., van Diest, PJ., et al. Metaanalysis of the concordance of histological grade of breast cancer between core needle biopsy and surgical excision specimen. Br J Surg, 2016, 103(6), p. 644–655.

6. Muller, R., Bresky, P. [Giant uterine fibroid - case report]. Ces Gynek, 2016, 81(1), s. 71–75.

7. Oelsner, G., Elizur, SE., Frenkel, Y., et al. Giant uterine tumors: two cases with different clinical presentations. Obstet Gynecol, 2003, 101(5 Pt 2), p. 1088–1091.

8. Ono, M., Qiang, W., Serna, VA., et al. Role of stem cells in human uterine leiomyoma growth. PLoS One, 2012, 7(5), p. e36935.

9. Segars, JH., Parrott, EC., Nagel, JD., et al. Proceedings from the Third National Institutes of Health International Congress on Advances in Uterine Leiomyoma Research: comprehensive review, conference summary and future recommendations. Hum Reprod Update, 2014, 20(3), p. 309–333.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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