-
Medical journals
- Career
- Contact
Vulvar melanoma
Authors: M. Arenbergerová 1; A. Fialová 1; E. Pojezná 1; P. Šefrnová 1; P. Arenberger 1; A. Havránková 2; T. Vedral 3; M. Šimková 4; M. Košťálová 4
Authors‘ workplace: Dermatovenerologická klinika 3. LF UK a FNKV, Praha, přednosta prof. MUDr. P. Arenberger, DrSc. 1; Gynekologicko-porodnická klinika 3. LF UK a FNKV, Praha, přednosta doc. MUDr. E. Kučera, CSc. 2; Chirurgická klinika 3. LF UK a FNKV, Praha, přednosta prof. MUDr. R. Gürlich, CSc. 3; Klinika nemocí kožních a pohlavních LF UK a FN, Hradec Králové, přednosta doc. MUDr. K. Ettler, CSc. 4
Published in: Ceska Gynekol 2013; 78(4): 351-355
Overview
Objective:
Malignant melanoma of the vulva is the second commonest vulval malignancy. This article will focus on three cases of vulvar melanoma which have been solved surgically with wide excision, sentinel lymph node biopsy and radical lymphadenectomy.Design:
Case report.Setting:
Department of Dermatovenerology 3rd Faculty of Medicine, Charles University, Faculty Hospital Královské Vinohrady, Prague.Methods:
Biopsy of the lesion creates a reliable diagnostic procedure. More frequently digital dermoscopy is used for the precise primary diagnostics and follow-up of pigment vulvar lesions.Results:
Vulvar melanoma has been variously estimated to account for between 3.6 and 10% of malignant vulvar neoplasms. An epidemiologic study revealed ratio of vulvar to skin melanoma 1 : 71.Conclusion:
New diagnostic methods such as digital dermoscopy or sentinel node biopsy bringing ever greater progress in precise diagnosis of patients with vulvar melanoma.Keywords:
vulvar melanoma – therapy – sentinel lymph node – dermoscopy
Sources
1. Abramova, L., Parekh, J., Irvin, WP., et al. Sentinel node biopsy in vulvar and vaginal melanoma: presentation of six cases and a literature review. Ann Surg Oncol, 2002, 9, p. 840–846.
2. Alexander, A., Harris, LM., Grossman, D., et al. Vulvar melanoma: Diffuse melanosis and metastasis to the placenta. J Am Acad Dermatos, 2004, 50, p. 293–298.
3. Creasman, WT., Phillips, JL., Menck, HR. A survay of hospital management practices for vulvar melanoma. J Am Coll Surg, 1999, 188, p. 670–675.
4. Ghurani, GB., Penalver, MA. An update on vulvar cancer. Am J Obstet Gynecol, 2001, 185, p. 294–299.
5. Gupta, D., Deavers, MT., Silva, EG., et al. Malignant melanoma involving the ovary: a clinicopathologic and immunohistochemical study of 23 cases. Am J Surg Pathol, 2004, 28, p. 771–780.
6. Gutzmer, R., Al Ghazal, M., Geerlings, H., et al. Sentinel node biopsy in melanoma delays recurrence but does not change melanoma-related survival: a retrospective analysis of 673 patients. Br J Dermatol, 2005, 153, p. 1137–1142.
7. Chang, AE., Karnell, LH., Menck, HR. The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84, 836 cases from the past decade. The American College of Surgeons Commision on Cancer and the American Cancer Society. Cancer, 1998, 83, p. 1664–1678.
8. Chung, A., Casey, M., Flannery, J., et al. Malignant melanoma of the vagina-report of 19 cases. Obstet Gynecol, 1980, 55, p. 720.
9. Kost‘álová, M., Kost‘ál, M., Ettler, K., et al. Melanoma clitoridis. Int J Dermatol, 2007, 46, p. 393–395.
10. Luxman, D., Jossiphov, J., Cohen, JR., et al. Uterine metastasis from vulvar malignant melanoma. A case report. J Reprod Med, 1997, 42, p. 244–246.
11. Omholt, K., Grafström, E., Kanter-Lewensohn, L., et al. KIT pathway alterations in mucosal melanomas of the vulva and other sites. 2011, 17, p. 3933–3942.
12. Ragnarsson-Olding, BK., Kanter-Lewensohn, LR., Lager-lof, B.,et al. Malignant melanoma of the vulva in a nationwide, 25-year study of 219 Swedish females: clinical observations and histopathologic features. Cancer, 1999, 86, p. 1273–1284.
13. Ragnarsson-Olding, BK., Nilsson, BR., Kanter-Lewen-sohn, LR., et al. Malignant melanoma of the vulva in a nationwide, 25-year study of 219 Swedish females: predictors of survival. Cancer, 1999, 86, p. 1285–1293.
14. Wechter, ME., Gruber, SB., Haefner, HP., et al. Vulvar melanoma: A report of 20 cases and review of the literature. J Am Acad Dermatol, 2004, 50, p. 554–562.
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
Article was published inCzech Gynaecology
2013 Issue 4-
All articles in this issue
- The injury of bladder without penetrate during the TVT surgery for stress incontinence
- Antibiotical prophylaxy in gynecology
- Umbilical cord blood soluble Toll-like receptor 2 in pregnancies complicated by preterm premature rupture of membranes
- Rapid detection of the most common chromosomal aneuploidies in the second-trimester amniotic fluid using QF-PCR
- Peripartal life-threating haemorrhage – intensive care and haematological treatment
- Nocturnal polyuria, treatment with desmopressin
- Current issues of assisted reproductionin the Czech Republic
- Theoretic and practical content of the clinical embryology
- Department of Gynecology and Obstetricin Faculty Hospital KV fifty years ago and today
- Diagnosis of minimal breast cancers
- Laparoscopic treatment of borderline ovarian tumorsin fertile women
- Cooperation between mammologist and radiodiagnostic in the management of mammary leasions in the University Hospital Kralovské Vinohrady
- Retrospective analysis of effectiveness of transvaginal ultrasound in the detection of ectopic pregnancy
- The importance of circulating tumor cells in the diagnostic and therapeutic process in ovarian cancer
- Position of targeted therapy in ovariancancer management
- Vulvar melanoma
- Czech Gynaecology
- Journal archive
- Current issue
- Online only
- About the journal
Most read in this issue- Vulvar melanoma
- Laparoscopic treatment of borderline ovarian tumorsin fertile women
- Nocturnal polyuria, treatment with desmopressin
- Peripartal life-threating haemorrhage – intensive care and haematological treatment
Login#ADS_BOTTOM_SCRIPTS#Forgotten passwordEnter the email address that you registered with. We will send you instructions on how to set a new password.
- Career