Authors: D. Koryntová; Martina Moosová; K. Řežábek; I. Pavelková; M. Mára Authors‘ workplace: MUDr. A. Martan, DrSc. ; Centrum asistované reprodukce, Gynekologicko-porodnická klinika VFN a 1. LF UK, Praha, přednosta prof. Published in: Ceska Gynekol 2005; 70(6): 435-439 Category: Original Article
Objective: Twin pregnancy is perceived as a suboptimal result of an IVF/ICSI cycle. The most effective way to reduce the number of twins in IVF/ICSI program is a single embryo transfer. The aim of our study was to compare the efficiency of elective single embryo transfer (eSET) and double embryo transfer (DET) in the couples with a very good prognosis of IVF/ICSI.
Design: Prospective case observational study.
Settings: Department of Obstetrics and Gynecology, Charles University, 1nd Medical Faculty and General Teaching Hospital, Prague, Czech republic.
Methods: A prospective study focused on eSET was performed between 1. 1. 2003 and 31. 12. 2004. We offered eSET or eDET to 331 IVF/ICSI couples who met the following inclusion criteria: age of the women
Results: Patients in both groups were not significantly different in age, number of oocytes retrieved and total number of quality embryos. In the eSET group, we achieved 30 clinical pregnancies and the pregnancy rate (PR) was 52.6%. In the eDET group, 151 clinical pregnancies were observed and the PR was 55.1%. Although the pregnancy rate in the eDET group was higher than in the eSET group, the difference between the two groups was not statistically significant. We have not observed any twin pregnancy (0.0%) in the eSET group while 57 (37.7%) twin pregnancies and 1 pregnancy with 3 embryos (0.4%) have been observed in the eDETgroup. This difference is statistically significant (P
Conclusion: In the group with a very good IVF/ICSI prognosis (women
Key words: single embryo transfer, pregnancy, twins, IVF/ICSI
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