Authors: B. Vavřinková 1; T. Binder 1; I. Vítková 2; J. Živný 1 Authors‘ workplace: Gynekologicko-porodnická klinika, VFN a 1. LF UK v Praze, přednosta prof. MUDr. J. Živný, DrSc. 2II. patologicko-anatomický ústav VFN a 1. LF UK v Praze, U nemocnice 4, přednosta prof. MUDr. C. Povýšil, DrSc. 1 Published in: Ceska Gynekol 2001; (5): 345-348 Category:
Objective: The aim of the study was to gauge the impact of drugs on placental changes in heroin and pervitin addict pregnant women as one of the influence factors supporting the lower birth-weight of the neonate.Design of the study: Prospective study.Setting: The Department of Gynaecology and Obstetrics and the Department of Pathology of the General Teaching Hospital and the 1st Medical Faculty of Charles University in Prague.Methods: The drugs-addict pregnant women were included in the study in the period between January 1998 till the end of the year 2000. We succeeded to concentrate in total 39 drug abused pregnant women and 39 their placentas and umbilcal cords were examined (19 heroin and 20 pervitin addict). The placentas were sent for the histological examination in total without the chemical fixation. There were 3 placental samples, 2 cord and 2 membranes samples examined. The controls groups were formed by non-abused pregnant women and their placentas by method of accidental choice.Results: We found the statistically significant higher incidence of placental and cords abnormalities in among the addict women compared to their non abused controls (P
Key words: heroin, pervitin, placenta
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